Sheng Wu Gong Cheng Xue Bao
October 2024
The xanthine dehydrogenase (XDH), a molybdenum-containing oxidoreductase belonging to the molybdenum hydroxylase flavoprotein family, has been identified in a variety of eukaryotes, bacteria, and archaea. XDH catalyzes the conversion of xanthine and hypoxanthine to uric acid, which then undergoes further reactions to form allantoin and allantoic acid. Studies have shown that XDH plays a role in various metabolic processes, including purine metabolism, nitrogen metabolism, hormone metabolism, reactive oxygen species metabolism, and responses to biotic and abiotic stresses.
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