Publications by authors named "Danuta Kozlowska-Rup"

Objectives: ABC transporters, P-gp, MDR3, BCRP and MRP1, can bind both endo- and exogenous ligands. The latter include immunosuppressive, anticancer sedative, anticonvulsant, antiparasitic and cardiovascular drugs, as well as HIV protease inhibitors and antibiotics. Protein transporters are also involved in tissue distribution of orally administered medicines in combination therapy for gestational diabetes mellitus (GDM) and could be used during GDM treatment.

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Background: Long-term treatment with gonadoliberin analogs is used to block the hypothalamic-pituitary-gonadal axis. The use of these agents is generally considered to be safe; however, some observations suggest the possibility of adverse effects.

Material/methods: We investigated whether a 3-months administration of a low dose (6 µg/kg b.

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Introduction: Body piercing and tattooing are accepted by a growing number of teenagers and young adults as a way of self-expressing. Some authors suggest association between body piercings/tattoos and early sexual initiation, higher number of sexual partners, or risky sexual behaviors.

Aim: The aim of the study was to evaluate sexual behaviors among young adults with body modifications (BMs)--tattoos and piercings.

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Both a pregnant woman and a fetus are exposed to a wide range of xenobiotics. Placenta provides the only link between the mother and the developing fetus. It plays a major protective role acting as a semi-permeable barrier to minimize fetal exposure to exogenous compounds.

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