Battery for fall risk assessment in older adult people-BARQ: analysis of reliability and objectivity.

Introduction: This study aims to address significant gaps in fall risk assessment among older adult individuals, using a methodological approach to develop and validate effective instruments.

Objective: To establish the objectivity and reliability of the Battery for Fall Risk Assessment in older adult people - BARQ.

Methodology: This descriptive, cross-sectional, exploratory study started with a preliminary version of BARQ, based on the Comprehensive Falls Risk Screening Instrument-CFRSI.

Antibiofilm, regenerative and bone homeostasis potential of the synergistic association of synoeca-MP peptide with chlorhexidine in oral cavity opportunistic infections.

Objective: Synoeca-MP is an antimicrobial peptide that belongs to the class of defense peptides, known for their antimicrobial and immunomodulatory properties. To evaluate in vitro the association between synoeca-MP peptide and chlorhexidine, regarding their antimicrobial and antibiofilm activities, saliva stability, effect on tissue repair, bone resorption processes, and mineralized matrix formation.

Design: Initially, the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and antibiofilm concentration were determined.

From overgrazed land to forests: assessing soil health in the Caatinga biome.

Overgrazing is the primary human-induced cause of soil degradation in the Caatinga biome, intensely threatening lands vulnerable to desertification. Grazing exclusion, a simple and cost-effective practice, could restore soils' ecological functions. However, comprehensive insights into the effects of overgrazing and grazing exclusion on Caatinga soils' multifunctionality are lacking.

The acute effect of bilateral cathodic transcranial direct current stimulation on respiratory muscle strength and endurance.

Introduction: Transcranial direct current stimulation (tDCS) is a non-invasive technique with therapeutic potential, especially in respiratory muscle training (RMT) in pathological conditions such as chronic obstructive pulmonary disease and heart failure.

Objective: To evaluate the effect of bilateral cathodic tDCS on respiratory muscle strength and endurance in healthy young and elderly women.

Methods: An experimental, randomized study with 80 participants divided into young and old women, subdivided into intervention and sham control groups.

Temporal trends in female firearm homicides across states in the Northeast of Brazil during the period 2000-2019.

This article aims to analyze temporal trends in female firearm homicides in the Northeast of Brazil during the period 2000-2019. We conducted an ecological study using data on firearm homicides of women aged 10 years and over obtained from the Mortality Information System. The population data were taken from the 2010 Census.

Depressive symptoms and associated factors among travestis and transsexuals: a cross-sectional study.

Objectives: to estimate the prevalence of depressive levels and their associated factors among transvestite and transsexual individuals.

Methods: this cross-sectional study involved 58 participants assisted by non-governmental organizations. The Beck Depression Inventory was utilized to assess levels of depression, complemented by a sociodemographic questionnaire and a questionnaire on experiences of violence.

Effect of Cantilever Extension on Bone Loss in Mandibular Complete-Arch Implant-Supported Fixed Prostheses with Three and Four Implants.

Purpose: To compare the peri-implant bone loss of mandibular complete-arch implant-supported fixed prostheses (FPSs) supported by three and four implants and to correlate with the size of the horizontal and vertical distal cantilever at prosthesis placement (T1) and after 1 year (T2).

Materials And Methods: A total of 72 external hexagon (EH) type implants were placed in 20 participants. Of these, 24 supported an FPS with three implants (G3I) and 48 with four implants (G4I).

The Space Omics and Medical Atlas (SOMA) and international astronaut biobank.

Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming increasingly relevant as more humans venture into space. Yet current frameworks for aerospace medicine are nascent and lag far behind advancements in precision medicine on Earth, underscoring the need for rapid development of space medicine databases, tools and protocols. Here we present the Space Omics and Medical Atlas (SOMA), an integrated data and sample repository for clinical, cellular and multi-omic research profiles from a diverse range of missions, including the NASA Twins Study, JAXA CFE study, SpaceX Inspiration4 crew, Axiom and Polaris.

Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer.

Aim: To investigate systemic regulators of the cancer-associated cachexia syndrome (CACS) in a pre-clinical model for lung cancer with the goal to identify therapeutic targets for tissue wasting.

Methods: Using the Kras/Lkb1 (KL) mouse model, we found that CACS is associated with white adipose tissue (WAT) dysfunction that directly affects skeletal muscle homeostasis. WAT transcriptomes showed evidence of reduced adipogenesis, and, in agreement, we found low levels of circulating adiponectin.

Salicylic Acid and Water Stress: Effects on Morphophysiology and Essential Oil Profile of .

The exogenous application of bioregulators, such as salicylic acid (SA), has exhibited promising outcomes in alleviating drought stress. Nevertheless, its impact on culantro ( L.) remains unexplored.

3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights into MFN-2 Mediated Changes.

Age-related atrophy of skeletal muscle, is characterized by loss of mass, strength, endurance, and oxidative capacity during aging. Notably, bioenergetics and protein turnover studies have shown that mitochondria mediate this decline in function. Although exercise has been the only therapy to mitigate sarcopenia, the mechanisms that govern how exercise serves to promote healthy muscle aging are unclear.

TIMP1 is an early biomarker for detection and prognosis of lung cancer.

Background: Lung cancer remains the major cause of cancer-related deaths worldwide. Early stages of lung cancer are characterized by long asymptomatic periods that are ineffectively identified with the current screening programs. This deficiency represents a lost opportunity to improve the overall survival of patients.

Decomposition and nutrient release of green manure biomass in a passion fruit orchard in the brazilian semiarid region.

Green manure decomposition and nutrient recycling improve soil quality and productivity of different crops, but information on irrigated fruit orchards in the Brazilian semi-arid region is still scarce. Decomposition and nitrogen, phosphate, and potassium release from the cut biomass of three green manure legumes (sunn hemp, pigeon pea and jack bean) placed in litterbags, and spontaneous vegetation grown for 90 days in the rows of a passion fruit orchard were followed for 150 days. Biomasses decreased exponentially, reaching 12 (sunn hemp) to 25% (jack beans and spontaneous vegetation) after 150 days.

Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer.

The cancer associated cachexia syndrome (CACS) is a systemic metabolic disorder resulting in loss of body weight due to skeletal muscle and adipose tissues atrophy. CACS is particularly prominent in lung cancer patients, where it contributes to poor quality of life and excess mortality. Using the Kras/Lkb1 (KL) mouse model, we found that CACS is associated with white adipose tissue (WAT) dysfunction that directly affects skeletal muscle homeostasis.

The Association between Physical Activity and Anxiety in Aging: A Comparative Analysis.

(1) Background: As the worldwide aging population is growing, there is a need to embrace the role of physical activity in the anxiety of older people. Objectives: To analyze anxiety in older people practitioners and non-practitioners of physical activity; (2) Methods: ample composed of 690 older people of both genders, unselected volunteers, residing in Brazil, present (as participants or observers) in selected street races in the state of Rio de Janeiro, Brazil, between 30 October 2019, and 12 March 2020. An instrument composed of the sociodemographic questionnaire and questions from the Beck Anxiety Inventory, BAI, and the Physical Activity Inventory for older people, Baecke-Old.

Toxicity assessment of sanitary landfill leachate before and after Fenton treatment process.

Sanitary landfills are widely accepted and promoted as the environmentally friendly way to properly dispose of solid waste. However, a harmful aspect is the leachate generation and management, which are currently recognized as one of the greatest challenges in the environmental engineering field. Due to the high leachate recalcitrance, Fenton treatment has been accepted as a viable and efficient treatment process, which significantly reduces the organic matter: 91 % of COD; 72 % of BOD5; and 74 % of DOC.

Effect of cantilever extension on bone loss in mandibular complete-arch implant-supported fixed prosthesis about 3 and 4 implants.

Statement Of Problem: The assessment of bone loss around implants has been widely studied, but the effect of cantilever length as a risk factor is not fully understood.

Purpose: The objective of this randomized controlled clinical trial was to compare the peri-implant bone loss of mandibular complete-arch implant-supported fixed prosthesis supported (FPS) by 3 and 4 implants and to correlate with the size of the horizontal and vertical distal cantilever at prosthesis installation (T1) and after one year (T2).

Materials And Methods: 72 external hexagon (EH) type implants were installed in 20 participants.

Drought stress mitigation by foliar application of L-carnitine and its effect on radish morphophysiology.

Unlabelled: Drought is the major abiotic stress limiting crop production worldwide, with drought events being expected to be harsher and more frequent due to the global warming. In this context, the development of strategies to mitigate the deleterious effects of drought, such as the use of biostimulants, is imperative. Radish is a globally cultivated root vegetable, with high nutritional and phytochemical value.