Publications by authors named "Danqiong Zhang"
Article Synopsis
- Herpes simplex virus type 1 (HSV-1) is linked to serious health issues including viral encephalitis and neonatal infections, prompting the exploration of vaccines for prevention.
- Researchers created a genetically modified strain of Lactococcus lactis (NZ3900-gD-IL-2-Fc) to express a protective viral antigen, aiming to enhance immune responses.
- Their findings showed that this recombinant vaccine significantly increased the production of antibodies and immune cell activity in mice, suggesting its potential effectiveness against HSV-1 infection.
The neonatal Fc receptor (FcRn) can transport IgG and antigen-antibody complexes participating in mucosal immune responses that protect the host from most pathogens' invasion via the respiratory, digestive, and urogenital tracts. FcRn expression can be triggered upon stimulation with pathogenic invasion on mucosal surfaces, which may significantly modulate the innate immune response of the host. As an immunoglobulin transport receptor, FcRn is implicated in the pathophysiology of immune-related diseases such as infection and autoimmune disorders.
View Article and Find Full Text PDFAcute myelogenous leukemia (AML) is a class of malignant tumors derived from hematopoietic stem or progenitor cells. The H2.0-like homeobox gene (HLX) encodes transcription factors that function in promoting normal hematopoietic cell proliferation and tumor immunity.
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