Regional alopecia and dermatitis due to Lodderomyces elongisporus in a North American porcupine (Erethizon dorsatum).

Background: Lodderomyces elongisporus is a yeast with a worldwide distribution that has been reported as a cause of infection in immunocompromised humans and in a dog that had been quilled by a porcupine.

Objectives: The objective of this report is to describe the clinical presentation, diagnosis and treatment of dermatitis caused by L. elongisporus in a North American porcupine (Erethizon dorsatum).

Looking back on 45 years of canine dermatology.

In June 2018, I was honored (and flabbergasted!) to receive the Kennel Club Charitable Trust's Lifetime Achievement Award for research in the field of canine health, sponsored by Vernon and Shirley Hill of Metro Bank, and administered by the Kennel Club Charitable Trust. I entered the arena of veterinary dermatology in 1971, a graduate of the University of California, Davis. I retired from Cornell University as the James Law Professor Dermatology Emeritus in 2016.

Resident lymphocytes in the dermis of the normal dorsolateral thoracic skin of alpacas.

Background: Small numbers of resident T lymphocytes are present in the dermis of normal skin of humans, cattle and sheep.

Hypothesis/objectives: We wanted to determine the prevalence, numbers and immunophenotype of lymphocytes in the dermis of healthy skin from alpacas.

Animals: Skin biopsy specimens were collected from the dorsolateral thorax of 31 alpacas with normal skin.

Scaling dermatosis in three dogs associated with abnormal sebaceous gland differentiation.

Background: Abnormal sebaceous gland differentiation, so-called 'sebaceous gland dysplasia', is a rare condition described in the dog and the cat. Although little is known about this condition, it is thought that a genetic defect causes abnormal sebaceous gland development. Clinically, this condition occurs in young cats and dogs and is characterized by variable degrees of adherent scale, hair casts, poor coat quality and hypotrichosis.

Resident lymphocytes in the epidermis and adnexal epithelia of normal dorsolateral thorax of alpacas.

A small population of resident T-lymphocytes is present in the normal epidermis of skin from humans, mice, sheep, and cattle. The objective of this study was to determine the prevalence of lymphocytes, CD3+ cells (T-lymphocytes) and CD79a+ cells (B-lymphocytes and plasma cells), in the epidermis and adnexal epithelia of alpacas. Skin-biopsy specimens from the normal skin of the dorsolateral thorax of 31 alpacas were examined histologically and immunohistochemically for the presence of CD3+ cells and CD79a+ cells in the epidermis and adnexal epithelia.

Feline dermatology at Cornell University: 1407 cases (1988-2003).

Medical records of 1407 cats with dermatologic diagnoses made at Cornell University teaching hospital from 1988 to 2003 were tabulated. We expressed the diagnoses as counts, percentages of the cats with dermatologic disease (1407) and percentages of all cats seen at the university hospital (22,135) during the same period. A total of 1887 diagnoses were made in the 1407 cats.

An open clinical trial on the efficacy of cetirizine hydrochloride in the management of allergic pruritus in cats.

Cetirizine hydrochloride was administered orally at 5 mg/cat, q24h, to 32 cats with allergic skin disease. Pruritus was reduced in 41% (13/32) of the cats. The antipruritic effect was repeatable and sustainable.

Alopecia areata in two black Angus cows.

Adult onset progressive alopecia and leukotrichia developed in 2 registered black Angus cows, aged 6 and 7 years. Histopathologic findings in skin were prominent melanin clumping and degeneration of matrix cells with formation of giant multinucleate cells within hair bulbs, accompanied by peribulbar melanin incontinence and fibrosis and dystrophic hair shafts. Intrabulbar and peribulbar lymphocytes were cluster of differentiation (CD)3-positive T cells.

Skin diseases in the alpaca (Vicugna pacos): a literature review and retrospective analysis of 68 cases (Cornell University 1997-2006).

This retrospective study describes 68 alpacas with skin diseases investigated from 1997 through 2006 at Cornell University. During this time period, 40 of 715 (5.6%) alpacas presented to the university hospital had dermatological diseases.

CD3+ and BLA.36+ cells do not occur in the epidermis and adnexal epithelia of normal skin from the dorsolateral trunk of cats.

A small population of resident T-lymphocytes is present in the normal epidermis of humans, mice, and rats. However, resident epidermal lymphocytes have not been reported in the normal skin of the cat. Skin-biopsy specimens from the normal skin of the dorsolateral trunk from 30 cats were examined histologically and immunohistochemically for the presence of lymphocytes, CD3+ cells, and BLA.

The microanatomy of healthy skin from alpacas (Vicugna pacos).

The microanatomy of healthy skin from 12 different body sites was investigated in 14 alpacas (Vicugna pacos). The microanatomy of alpaca skin is typical of domestic animal skin in general, and closely resembles that from llamas.

Prevalence of apoptotic epidermal keratinocytes in eosinophilic dermatoses of the cat: a retrospective light-microscopic study of 145 skin-biopsy specimens.

A retrospective light-microscopic study was performed on skin-biopsy specimens from 145 cats with eosinophilic inflammatory dermatoses in order to determine the prevalence of apoptotic epidermal keratinocytes (AKs), the prevalence of eosinophils in close proximity to AKs, and whether there was a difference in the prevalence of AKs or the prevalence of eosinophils in close proximity to AKs based on histopathological reaction pattern. Overall, 62/145 (43%) specimens had AKs. Of the cases in which AKs were seen, 18% had eosinophils in close proximity to the AKs.

Infiltrative lymphocytic mural folliculitis: a histopathological reaction pattern in skin-biopsy specimens from cats with allergic skin disease.

This study was conducted to determine the prevalence of infiltrative lymphocytic mural folliculitis (ILMF) in skin-biopsy specimens from 354 cats with various inflammatory dermatoses and from 33 cats with normal skin. Although ILMF was present in 33/47 dermatoses evaluated, the prevalence of ILMF in allergic dermatoses (116/172 cats; 67%) was significantly greater than that in non-allergic dermatoses (61/182 cats; 33%). Cats with allergic dermatoses had a 4.

Frequency of apoptotic keratinocytes in the feline epidermis: a retrospective light-microscopic study of skin-biopsy specimens from 327 cats with normal skin or inflammatory dermatoses.

A retrospective light-microscopic study was performed on 294 biopsy specimens of haired skin from cats with various feline inflammatory dermatoses and specimens from cats with normal skin. Conditions expected to frequently have apoptotic epidermal keratinocytes (AKs) (including erythema multiforme, systemic lupus erythematosus, thymoma-associated exfoliative dermatitis, solar dermatitis, and viral dermatopathies) were found to have significantly more AKs than other types of inflammatory dermatoses. Nevertheless, we found more than two AKs in many skin-biopsy specimens from inflammatory conditions not expected to have frequent AKs (especially those from ectoparasitic dermatoses).

Diffuse cutaneous mastocytosis in a newborn calf.

Previously reported cases of congenital cutaneous mast cell tumours in calves were characterized by multiple discrete nodules. The calf presented herein is, to the authors' knowledge, the first documented case of congenital diffuse cutaneous mastocytosis. The entire skin was thickened and wrinkled with particularly prominent skin folds on the head, ventrum, and legs.

Apparent clinical resolution of pinnal actinic keratoses and squamous cell carcinoma in a cat using topical imiquimod 5% cream.

Imiquimod is a topical immune response modifier and stimulator used in humans to treat a number of cutaneous neoplasms. This case report describes a cat with actinic keratoses and squamous cell carcinoma of the pinnae. The pinnal lesions were treated with topical 5% imiquimod three times per week.