Publications by authors named "Danny Paysen"

Article Synopsis
  • Research on 17β-estradiol (E2) has primarily focused on the CA1 and CA3 regions of the hippocampus, leaving the dentate gyrus (DG) largely unexplored.
  • The study found high levels of estrogen receptor (ER)α in the DG, particularly in Cajal-Retzius (CR) cells, and a reduction in spine synapses following E2 synthesis inhibition, indicating a potential role of E2 in synapse maintenance.
  • Exogenous E2 increased reelin expression in CR cells, an essential factor for neuronal function, while inhibition of its synthesis decreased reelin levels, highlighting E2’s crucial role in synaptic regulation and neuronal differentiation in the DG.
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