Publications by authors named "Danny M Skyba"

Objectives: To evaluate intra- and interobserver reproducibility of shear wave elastography (SWE) for breast masses.

Methods: For intraobserver reproducibility, each observer obtained three consecutive SWE images of 758 masses that were visible on ultrasound. 144 (19%) were malignant.

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Objective: We sought to determine the prognostic value of myocardial contrast echocardiography (MCE) in patients with known or suggested coronary artery disease compared with technetium-99m sestamibi single photon emission computed tomography (SPECT)-myocardial perfusion imaging (MPI).

Background: The prognostic value of SPECT-MPI is well established for patients with coronary artery disease. It is less well defined by MCE.

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Objectives: The purpose of this study was to compare the assessment of myocardial perfusion by myocardial parametric quantification (MPQ) with technetium-99m sestamibi single-photon emission computed tomographic (SPECT) imaging in humans.

Background: Accurate visual interpretation of myocardial contrast echocardiographic (MCE) images is qualitative and requires considerable experience. Current computer-assisted quantitative perfusion protocols are tedious and lack spatial resolution.

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Manual endocardial tracing using Simpson's method (MANUAL SIMP) provides an accurate assessment of left-ventricular ejection fraction (LVEF). We have previously demonstrated in patients who are difficult to image: (1) the incremental accuracy of contrast-enhanced power harmonic imaging and MANUAL SIMP in the calculation of LVEF; and (2) the use of intravenous contrast-combined MANUAL SIMP was the most accurate method of LVEF determination. However, MANUAL SIMP is time-consuming, requires accurate planimetry of the endocardial borders, and is difficult to apply routinely in the clinical situation.

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