Publications by authors named "Danny David Jonigk"
Article Synopsis
- A young man was admitted to a medical center with shortness of breath and high troponin levels, following his first dose of the BioNTech mRNA vaccine.
- He was diagnosed with giant cell myocarditis and received immunosuppressive treatment.
- The report discusses the rare occurrence of myocarditis post-mRNA vaccination and the associated treatment strategies based on current guidelines.
Cardiac fibroblasts constitute the major cell type of the murine and human heart. Once activated, they contribute to an excessive deposition of extracellular matrix (ECM) leading to cardiac fibrosis and subsequently organ dysfunction. With the exception of the pulmonary drugs, nintedanib and pirfenidone, drugs specifically targeting anti-fibrotic pathways are scarce.
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