Publications by authors named "Dannika Bakker"
Ischemic Monomelic Neuropathy: The Case for Reintroducing a Little-Known Term.
Can J Neurol Sci
September 2020
Ischemic monomelic neuropathy (IMN) is a little-known, painful axonal neuropathy, secondary to vascular occlusion or steal phenomenon. It typically occurs after vascular bypass, hemodialysis fistulization, or diabetic microvascular disease in the absence of significant clinical features of ischemia. There is limited literature to assist in the characterization and diagnosis of this condition.
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- * The protein EspD is essential for creating a pore in the host cell membrane and can integrate into lipid bilayers, but requires specific conditions (anionic phospholipids and acidic pH) for pore formation.
- * Research indicates that EspD forms a sizable oligomeric structure (about 280-320 kDa) comprised of multiple subunits, with specific transmembrane features that allow it to penetrate lipid layers.
The Amphibian Metamorphosis Assay (AMA), developed for Xenopus laevis, is designed to identify chemicals that disrupt thyroid hormone (TH)-mediated biological processes. We adapted the AMA for use on an ecologically-relevant North American species, the Pacific tree frog (Pseudacris regilla), and applied molecular endpoints to evaluate the effects of the antibacterial agent, triclosan (TCS). Premetamorphic (Gosner stage 26-28) tadpoles were immersed for 21 days in solvent control, 1.
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