Publications by authors named "Danna Zhao"

Antibiotic resistance genes (ARGs) are widespread contaminants that pose significant threats to public health. Rivers play a crucial role in the dissemination of ARGs within the aquatic environment. However, there are limitations in the current research on the differentiation of intracellular ARGs (iARGs) and extracellular ARGs (eARGs) in river water.

View Article and Find Full Text PDF

Background: With the transformation of China's economy and society, the floating population has also shown a new development trend, from individual migration to co-migration with family members. In 2020, among the 376 million floating population, the population flowing to cities and towns was 330 million, accounting for nearly 88.1%.

View Article and Find Full Text PDF

Oceans cover over 71% of the Earth's surface and play crucial roles in regulating the global climate. In the marine boundary layer, the levels of volatile organic compounds (VOCs) have been shown to have positive relations with the marine algal biomass, indicating that the marine biological activities can be an important biogenic VOCs (BVOCs) source. The emitted BVOCs will enhance the formation of secondary organic aerosols, and perturb the radiative forcing, which ultimately affects the climate.

View Article and Find Full Text PDF

Owing to their unique advantages, single-electrode triboelectric nanogenerators (SETENGs) have gained wide attention and have been applied in myriad areas, especially in the burgeoning flexible/wearable electronics. However, there is still a lack of a clear understanding of SETENGs. For example, previous simulation models generally put the reference electrode perpendicularly below the working part, but in practice, the reference electrode is designed in various scenarios and noticeable differences in outputs often occur when the reference electrode changes.

View Article and Find Full Text PDF

As algae are extremely sensitive to heavy-metal ions and can be critical biological indicators in the heavy-metal toxicity analyses conducted by environmental health researchers, this paper explores the sensitivity to temporal toxicity of three species of green algae: , , and . The method of time-dependent microplate toxicity analysis was used to systematically investigate the changes in the toxicities of the three green-algae species induced by different concentrations of cadmium (Cd). The chlorophyll content, antioxidant enzyme activity, and malondialdehyde (MDA) content in the algae were analyzed to explore the mechanism of Cd toxicity after 96 h of exposure.

View Article and Find Full Text PDF

Flexible temperature sensors can be attached to the surface of human skin or curved surfaces directly for continuous and stable data measurements, and have attracted extensive attention in myriad areas. Carbon nanomaterials possess great potential for temperature sensing, and flexible temperature sensors based on carbon nanomaterials have demonstrated unique advantages such as high sensitivity, fast response, good mechanical adaptability, low-cost fabrication processes, high cycling stability and reliability. In this review, the working mechanisms, device structures, material compositions, fabrication technologies, temperature sensing properties, the crucial roles of carbon nanomaterials, specific advantages and existing limitations of different types of flexible temperature sensors based on carbon nanomaterials are comprehensively elaborated and discussed.

View Article and Find Full Text PDF

It has been demonstrated that defect engineering is an effective strategy to enhance the activity of materials. Herein, a polycrystalline GaN porous layer (PGP) with high catalytic activity was grown by self-assembly on GaN-coated sapphire substrate by using low-temperature (LT) MOCVD growth. Without doping, LT growth can significantly improve the activity and electrical conductivity of PGP, owing to the presence of rich N-vacancies (∼10 cm).

View Article and Find Full Text PDF

Purpose: The goal of the study was to elucidate the structure of a new degradant (1,3'-Dimer), generated in the stability testing of ropinirole extended-release tablets, and the formation mechanism of 1,3'-Dimer and its isomer (3,3'-Dimer).

Methods: The strategy of combining LC-PDA/UV-MS (n = 1, 2) and NMR in conjunction with mechanism-based forced degradation study was employed to identify the structure of the unknown degradant and the formation mechanism of this dimeric degradant as well as its isomer, 3,3'-Dimer. The forced degradation was conducted by treating ropinirole API with formaldehyde under alkaline catalysis.

View Article and Find Full Text PDF

Objective: This study aimed to explore the predictive value of microRNA (miR)-125a and miR-125b for sepsis risk, and their correlations with inflammation, disease severity, and 28-day mortality in sepsis patients.

Methods: Totally, 150 sepsis patients and 150 healthy controls (HCs) were enrolled. Plasma samples were separated from blood samples obtained from sepsis patients and HCs to detect miR-125a and miR-125b expressions by real-time quantitative polymerase chain reaction.

View Article and Find Full Text PDF

Objective: To investigate the prevalence, risk factors and mortality rate for acute respiratory distress syndrome (ARDS) in Chinese patients with sepsis.

Methods: This prospective study was based on data from consecutive patients with sepsis who attended Cangzhou Central Hospital between January 2017 and May 2019 and who developed ARDS. Multivariate logistic regression was used to identify risk factors associated independently with ARDS development.

View Article and Find Full Text PDF

Objective: This study was conducted to explore the association of microRNA (miR)-125a and miR-125b with acute respiratory distress syndrome (ARDS) risk and to investigate their correlation with clinical characteristics and prognosis in sepsis patients.

Methods: Totally 150 sepsis patients admitted to our hospital were consecutively enrolled and another 150 healthy subjects were enrolled as healthy controls (HCs). Their blood samples were collected for miR-125a and miR-125b detection by real-time quantitative polymerase chain reaction.

View Article and Find Full Text PDF

Enamel grinding is a critical dental surgery process. However, tooth damage during the process remains a significant problem. Grinding forces, burr wear, and surface quality were characterised in relation to grinding speed, enamel orientation, grinding depth, and burr grit grain size.

View Article and Find Full Text PDF

Self-powered skin sensors have attracted significant attention in recent years due to their great potential in medical care, robotics, prosthetics, and sports. More importantly, self-powered skin sensors do not need any energy-supply components like batteries, which allows them to work sustainably and saves them the trouble of replacement of batteries. The self-powered skin sensors are mainly based on energy harvesters, with the device itself generating electrical signals when triggered by the detected stimulus or analyte, such as body motion, touch/pressure, acoustic sound, and chemicals in sweat.

View Article and Find Full Text PDF

Direct-bridge growth of aligned GaN nanowires (NWs) over the trench of GaN-coated sapphire substrate was realized in which the issues of parasitic deposition and resultant bypass current were resolved by combining the novel shadowing effect of the deep trench with the surface-passivation effect of the SiO coating. Due to the robust connection and the absence of a contact barrier in bridging NWs, the intrinsic sensing properties of the NW itself can be obtained. For the first time, the gas-sensing properties (e.

View Article and Find Full Text PDF

Aromatic halogenated chemicals are an unregulated class of byproducts (DBPs) generated from disinfection processes in the water environment. Information on the toxicological interactions, such as antagonism and synergism, present in DBP mixtures remains limited. This study aimed to determine the toxicological effects of aromatic halogenated DBP mixtures on the freshwater bacterium Vibrio qinghaiensis sp.

View Article and Find Full Text PDF

During the related substances testing of mirabegron extended release tablets, an unknown peak was observed in HPLC chromatograms in a level exceeding the identification threshold. By using a strategy that combines LC-PDA/UV-MS with mechanism-based stress studies, the unknown peak was rapidly identified as cyanomethyl mirabegron, a solution degradant that is caused by a Strecker-like reaction between the API, formaldehyde (an impurity in PEG), and HCN (an impurity in HPLC grade acetonitrile). The mechanism of the solution degradation chemistry was verified by stressing mirabegron with formaldehyde and trimethylsilyl cyanide (TMSCN, a synthetic reagent that generates HCN upon contact with water), in which the secondary amine group of mirabegron first reacts with formaldehyde to form the iminium ion intermediate; the latter then undergoes a nucleophilic attack by cyanide to yield the cyanomethyl mirabegron.

View Article and Find Full Text PDF

Objective: This study aimed to explore the effects of arterial lactate as a predictor of mortality in patients with paraquat (PQ) poisoning.

Methods: The databases PubMed, EMBase, Web of Science, ScienceDirect, Cochrane library, and studies published until 31 February 2018 were searched. The data were extracted to perform pooled analysis, heterogeneity testing, sensitivity analysis, publication bias analysis, and Fagan plot analysis.

View Article and Find Full Text PDF

Six common heavy metals (Ni, Fe, Zn, Pb, Cd, and Cr) in the water environment were selected to present five groups of binary mixture systems (Ni-Fe, Ni-Zn, Ni-Pb, Ni-Cd, and Ni-Cr) through a direct equipartition ray design. Microplate toxicity analysis based on Chlorella pyrenoidosa measured the 96-h joint toxicities of the binary mixtures. Toxicity interaction of the binary mixture was analyzed by comparing the observed toxicity data with the reference model (concentration addition).

View Article and Find Full Text PDF

In a craniotomy, the milling cutter is one of the most important cutting tools. The operating performance, tool durability and cutting damage to patients are influenced by the tool's sharpness, intensity and structure, whereas the cutting characteristics rely on interactions between the tool and the skull. In this study, an orthogonal cutting experiment during a craniotomy of fresh pig skulls was performed to investigate chip formation on the side cutting and face cutting of the skull using a high-speed camera.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: