Publications by authors named "Danli Meng"
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by arterial and/or venous thrombosis, pathological pregnancies and persistent antiphospholipid antibodies. The occurrence and development of APS are complex and associated with immune disorders, with its prognosis remaining uncertain. Owing to its pathogenesis, anticoagulation therapy is the primary treatment for patients with APS.
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- Rapidly progressive interstitial lung disease (RP-ILD) is a serious complication in patients with idiopathic inflammatory myopathy (IIM), often leading to poor outcomes, making the need for effective treatments essential.
- Plasma exchange (PE) may help by quickly removing harmful substances from the blood, and this study assesses its effectiveness when combined with immunosuppressants in improving survival rates and reducing inflammatory markers.
- Results showed an 80% survival rate at 6 months for patients undergoing PE, which was significantly better than for those not receiving PE, suggesting its potential as a beneficial treatment option for IIM-RP-ILD.
Background: Osteoporosis with pathological fractures is a significant public health issue, contributing to morbidity, disability, diminished quality of life, and increased mortality. Understanding mortality trends related to this condition is crucial for developing effective interventions to reduce mortality and improve healthcare outcomes. This study aimed to analyze trends and causes of death associated with osteoporosis and pathological fractures in the United States using a multi-cause approach.
View Article and Find Full Text PDFSystemic lupus erythematosus (SLE) is a multi‑system chronic autoimmune disease with a complex occurrence and development process, associated with immune disorders, uncertain prognosis, and treatment modalities which vary by patient and disease activity. At present, the clinical treatment of SLE mainly focuses on hormones and immunosuppressants. In recent years, the research on new treatment strategies for SLE has been booming, and strong preclinical results and clinical research have promoted the development of numerous drugs (such as rituximab and orencia), but numerous of these drugs have failed to achieve effectiveness in clinical trials, and there are some adverse reactions.
View Article and Find Full Text PDFObjective: To investigate predictive factors for irreversible organ damage in systemic sclerosis (SSc) and establish a nomogram model.
Methods: This retrospective study included patients with SSc who were treated at our hospital between March 2013 and March 2023. Irreversible organ damage included heart failure, respiratory failure, renal failure, and gangrene of the hands and feet.