Cardiovascular disease (CVD) is a leading cause of death and disability worldwide, and its incidence and prevalence are increasing in many countries. Modeling of CVD plays a crucial role in understanding the trend of CVD death cases, evaluating the effectiveness of interventions, and predicting future disease trends. This study aims to investigate the modeling and forecasting of CVD mortality, specifically in the Sindh province of Pakistan.
View Article and Find Full Text PDFIntroduction: Indolent non-Hodgkin's lymphomas (NHLs) are a diverse category of malignancies characterized by a chronic relapsing-remitting disease course. In the modern era, patients usually receive a combination of bendamustine plus rituximab as the initial therapy, otherwise known as an R-Benda regimen. While clinical trials have demonstrated R-Benda to be superior to other regimens, our study aims to provide insight into real-world outcomes of R-Benda therapy.
View Article and Find Full Text PDFClin Appl Thromb Hemost
June 2024
Objective: To examine the effectiveness of rivaroxaban compared to enoxaparin in patients diagnosed with cancer and venous thromboembolism.
Methods: A search of Pub Med, Scopus, and Google Scholar, from inception through April 2023 was conducted. Articles comparing rivaroxaban with enoxaparin in patients with cancer and VTE/PE/DVT were included.
Objective: The aim of this study was to identify the frequency, form, and underlying factors contributing to gender inequity experienced by medical undergraduates and assess its influence on their career choices.
Method: This was a cross-sectional, retrospective survey with a 100% response rate. This survey was distributed among medical students of clinical years in Karachi's private and government medical colleges from September 10, 2021-March 30th, 2022.
Background Of Study: Over the past few decades, the utilization of Artificial Intelligence (AI) has surged in popularity, and its application in the medical field is witnessing a global increase. Nevertheless, the implementation of AI-based healthcare solutions has been slow in developing nations like Pakistan. This unique study aims to assess the opinion of clinical specialists on the future replacement of AI, its associated benefits, and its drawbacks in form southern region of Pakistan.
View Article and Find Full Text PDFImmune checkpoint inhibitors (ICIs) are now being widely used for the treatment of various malignancies, but they have a distinctive set of side effects due to the overactivation of the immune system, which is important to recognize. Capillary leak syndrome (CLS) is a rare but potentially life-threatening side effect of ICIs that causes a significant increase in the permeability of capillaries, leading to the leakage of plasma-containing proteins from these small vessels. This condition results in several clinical features, including edema, hypotension, hypoalbuminemia, and hemoconcentration.
View Article and Find Full Text PDFBackground: Gross domestic product (GDP) serves as a crucial economic indicator for measuring a country's economic growth, exhibiting both linear and non-linear trends. This study aims to analyze and propose an efficient and accurate time series approach for modeling and forecasting the GDP annual growth rate (%) of Saudi Arabia, a key financial indicator of the country.
Methodology: Stochastic linear and non-linear time series modeling, along with hybrid approaches, are employed and their results are compared.
Background: Prediction models have gained immense importance in various fields for decision-making purposes. In the context of tennis, relying solely on the probability of winning a single match may not be sufficient for predicting a player's future performance or ranking. The performance of a tennis player is influenced by the timing of their matches throughout the year, necessitating the incorporation of time as a crucial factor.
View Article and Find Full Text PDFObjective: This study aims to elaborate the incidence, types, and characteristics of ligamentous knee injuries accompanying femoral-shaft fractures and their association with demographic data, fracture characteristics, and injury mechanism.
Methods: This multi-center-prospective-observational study examined patients in the Shaheed Mohtarma Benazir Bhutto Institute of Trauma and Civil Hospital orthopedic wards. Using the consecutive sampling technique, 146 patients with femoral-shaft fractures were recruited, and scrutinized to determine the presence of ligamentous knee injury, through an evaluation form encompassing patients' demographic data, fracture characteristics, knee examinations, and confirmed through magnetic resonance imaging.
Background: PlayerUnknown's battlegrounds (PUBG), a widely played multiplayer online game, has sparked interest and concern regarding its impact on players. This study explored the relationship between factors such as cultivation level, motivation, religious engagement, gaming disorder, and addiction among PUBG players.
Methods: This study employed a convenience sampling technique to select a sample of 500 PUBG players.
Objective: To measure the severity of allergic rhinitis (AR) and different types of headaches in patients with septal deviation before and after septoplasty.
Methods: This multicentre, prospective, longitudinal, observational study enrolled patients with deviated nasal septum, nasal symptoms and headaches associated with persistent AR lasting at least 2 months without resolution. The nasal obstruction evaluation (NOSE) scale, immunoglobulin-E (Ig-E) levels and visual analogue scale (VAS) for headache pain severity were evaluated before and after septoplasty using Wilcoxon signed-rank test.
Background: Despite its profound impact on the oncologic outcomes of rectal cancer, the most optimal surgical approach to total mesorectal excision (TME) has not been identified yet. All previous meta-analyses on this subject have been based on observational studies. This meta-analysis was conducted to assess the surgical and oncologic outcomes of laparoscopic TME (LaTME) compared to trans-anal TME (TaTME), utilizing only randomized controlled trials.
View Article and Find Full Text PDFObjectives: The rising of new cases and death counts from the mpox virus (MPV) is alarming. In order to mitigate the impact of the MPV it is essential to have information of the virus's future position using more precise time series and stochastic models. In this present study, a hybrid forecasting system has been developed for new cases and death counts for MPV infection using the world daily cumulative confirmed and death series.
View Article and Find Full Text PDFCarbon dioxide (CO2) emissions have become a critical aspect of the economic and sustainable development indicators of every country. In Pakistan, where there is a substantial increase in the population, industrialization, and demand for electricity production from different resources, the fear of an increase in CO2 emissions cannot be ignored. This study explores the link that betwixt CO2 emissions with different significant economic indicators in Pakistan from 1960 to 2018 using the autoregressive distributed lag (ARDL) modelling technique.
View Article and Find Full Text PDFOvarian carcinosarcoma (OCS) is an uncommon and highly aggressive subtype of ovarian cancer. This form of cancer is characterized by limited treatment options and a poor prognosis. In this report, we present a case study of a 64-year-old female diagnosed with stage III OCS, who underwent debulking surgery and adjuvant chemotherapy, followed by immunotherapy, with encouraging outcomes.
View Article and Find Full Text PDFBackground: With an ever-evolving digital and virtual world hastened by the COVID-19 pandemic, prospective colon and rectal surgery fellowship applicants must rely on online sources of information, such as websites, rather than in-person visits to fellowship programs. This study analyzes and evaluates the content and accuracy of colon and rectal surgery fellowship program websites.
Methods: The Fellowship and Residency Electronic and Interactive Database website provides a complete collection of colon and rectal surgery fellowship websites based in the USA.
J Environ Public Health
February 2023
Pakistan is considered among the top five countries with the highest CO emissions globally. This calls for pragmatic policy implementation by all stakeholders to bring finality to this alarming situation since it contributes greatly to global warming, thereby leading to climate change. This study is an attempt to make a comparative analysis of the linear time series models with nonlinear time series models to study CO emission data in Pakistan.
View Article and Find Full Text PDFBackground: Awareness of rights is a precondition to establishing rule of law in society. Sexual and Reproductive Health and Rights (SRHR) are closely knitted in the human rights framework as they overlap with other human rights such as the right to health and life. However, awareness about these rights remains a challenge.
View Article and Find Full Text PDFBackground: Herbal medicines, derived from medicinal plants, are among the most popular alternative remedies around the globe. In Saudi Arabia, herbal medicines are extensively used by public as part of the culture as well as religious norms. Therefore, this study aimed to evaluate knowledge, attitudes, and practices regarding herbal medicines among the general population in Saudi Arabia.
View Article and Find Full Text PDFBackground: Monkeypox virus is gaining attention due to its severity and spread among people. This study sheds light on the modeling and forecasting of new monkeypox cases. Knowledge about the future situation of the virus using a more accurate time series and stochastic models is required for future actions and plans to cope with the challenge.
View Article and Find Full Text PDFBiomed Res Int
September 2022
Background: The use of birth control methods is influenced by complex and competing socioeconomic and demographic factors. Regardless of the complexity of the behavioral approach of women, the utility of contraceptive methods in providing the opportunity of choice is well paired. This study examined the factors driving the usage of contraception and the impact of contraceptive practices on population growth in Pakistan.
View Article and Find Full Text PDFBackground: The number of regular smartphone users has increased dramatically worldwide. Headaches, followed by sleep difficulties, forgetfulness, dizziness, and other ailments, are among the most prevalent complaints among smartphone users during or after use. In addition, migraine is a debilitating disease and is the world's second leading cause of disability.
View Article and Find Full Text PDF(1) Background: The study aims to examine the use of cell phones on physical and mental health status and their impact on personality among university students. (2) Methods: A cross-sectional study was conducted using a semi-structured questionnaire. The association of physical and mental health variables with the demographic variables was examined using Pearson's correlation and χ-test.
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