Neural dynamics in the orbitofrontal cortex reveal cognitive strategies.

Behavior is sloppy: a multitude of cognitive strategies can produce similar behavioral read-outs. An underutilized approach is to combine multifaceted behavioral analyses with neural recordings to resolve cognitive strategies. Here we show that rats performing a decision-making task exhibit distinct strategies over training, and these cognitive strategies are decipherable from orbitofrontal cortex (OFC) neural dynamics.

Ensuring Community Engagement in Disease Surveillance: The Municipal Case Investigation and Contact Tracing System for COVID-19 in Puerto Rico.

To describe the implementation of a novel disease surveillance model in Puerto Rico, the Municipal Case Investigation and Contact Tracing System for COVID-19, established during the pandemic as the primary response. We analyzed data from July 2020 to June 2021, including all COVID-19 cases reported by public and private laboratories in Puerto Rico to describe the accomplishments and limitations of the surveillance. During the first year, the system was successfully implemented in all Puerto Rican municipalities, collecting data on more than 132 000 confirmed COVID-19 cases.

Development of a computational model of glucose toxicity in the progression of diabetes mellitus.

Diabetes mellitus is a disease characterized by a range of metabolic complications involving an individual's blood glucose levels, and its main regulator, insulin. These complications can vary largely from person to person depending on their current biophysical state. Biomedical research day-by-day makes strides to impact the lives of patients of a variety of diseases, including diabetes.