Chronic Fatigue Exhibits Heterogeneous Autoimmunity Characteristics Which Reflect Etiology.

Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is considered to be associated with post-viral complications and mental stress, but the role of autoimmunity also remains promising. A comparison of autoimmune profiles in chronic fatigue of different origin may bring insights on the pathogenesis of this disease. Thirty-three patients with CFS/ME were divided into three subgroups.

The direct costs of epilepsy in Russia. A prospective cost-of-illness study from a single center in Moscow.

Objective: The objective of this study was to investigate prospectively the direct costs of epilepsy in Russia, taking a patient perspective and a bottom-up approach.

Methods: The study was conducted in adolescents and adults with epilepsy seen in the ambulatory services of a city hospital in Moscow. Patients were assigned to different prognostic categories: newly diagnosed epilepsy; epilepsy in remission for 2+years; epilepsy in remission for <2years or with occasional seizures; active, nondrug-resistant epilepsy; drug-resistant epilepsy; and drug-resistant epilepsy in surgical candidates.

[The results of the multicenter pharmaco-epidemiological observational project on the use of mydocalm in the treatment of pain syndromes with the muscle spasm].

The prospective multicenter open noncomparative pharmaco-epidemiological observational project on the use of mydocalm in real clinical practice has been completed in 2013. The project has been performed in 2090 clinical/rehabilitation settings in 284 cities of 13 countries using the results of 35,383 patients. The project aimed to assess the safety of treatment (percentage of patients with adverse-effects) and pain relieving efficacy as well as patient's satisfaction with the treatment.

[Laser iridectomy and anatomical and functional parameters in primary angle-closure glaucoma].

The paper discusses literature data on the effectiveness of laser iridectomy in patients with primary angle-closure glaucoma. The main methods of anatomical and functional assessment and changes evaluation are reviewed.

[Video-assisted surgery of Hirschsprung's disease in children].

Results of the laparoscopic treatment of 36 patients with Hirschsprung's disease were analyzed. The majority of patients were the newborns or before 12 months old. The use of laparoscopy permitted a full-fledged topical diagnostics, aganglionosis zone identification, gut mobilization and voiding.

[Restoration of the colon continuity in patients with ascendostomy after Gartmann operation with rectal supraanal resection].

Results of performance of reconstructive-restoration operation in 7 patients with ascendostomy were analyzed. Of them in 4 as the first stage supraanal rectal resection was performed and in 3 - Gartmann operation. There was proposed the method for colonic continuity restoration after Gartmann operation performance, in which pancreatic stump is mobilized along its posterior wall, securing nutrient vessels up to highest point and lower surface of the pelvic peritoneum sheet.

[Intraoperative complications in performance of reconstruction-restoration interventions in patients, to whom one-barrel colostomy was constructed].

Results of performance of reconstruction-restoration operations in 208 patients with one-barrel colostomy were analyzed. Earlier operation according to Hartmann procedure modification was performed in 138 (66.3% +/- 3.

[Problems of prevention of mental disorders in school children].

The paper covers various aspects of schoolchildren's mental adaptation. The study has indicated that mental health is worse in 6th-9th-form pupils than that in junior schoolchildren. There is a relationship of the deviant behavior of schoolchildren and their mental health.

[Diagnosis, surgical treatment and evaluation of adaptation possibilities of women with congenital abnormalities and fibromyoma of the uterus].

The results of radiological, endoscopical, ultrasonic methods of examination, performed in 52 women of reproductive age with the inborn developmental failures, of uterus and in 69 with fibromyoma of uterus, were analysed. The revealing of organic changes in uterus and the small pelvis organs made it possible to perform successful surgical treatment, to restore reproductive function and to stabilize the adaptational possibilities of the women organism.