Publications by authors named "Danika R Klaus"

Article Synopsis
  • Inflammation significantly impacts depression, especially in individuals with chronic inflammatory diseases, leading to a higher prevalence of depression compared to the general population.
  • A study with 26 adults (mostly with asthma) examined how their brain connectivity related to depressive symptoms during periods of heightened inflammation triggered by allergens.
  • Results showed that individuals with higher depressive symptoms experienced a decline in brain connectivity, while those with lower symptoms maintained or improved connectivity, suggesting potential resilience strategies in the brain's response to inflammation.
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Background: The staggering morbidity associated with chronic inflammatory diseases can be reduced by psychological interventions, including Mindfulness-Based Stress Reduction (MBSR). Proposed mechanisms for MBSR's beneficial effects include changes in salience network function. Salience network perturbations are also associated with chronic inflammation, including airway inflammation in asthma, a chronic inflammatory disease affecting approximately 10% of the population.

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Background: Psychological distress and comorbid psychopathology contribute to exacerbation risk in patients with asthma. Thus, interventions designed to reduce stress and improve emotion regulation, such as Mindfulness-Based Stress Reduction (MBSR), may augment standard care. Few studies have addressed this question and a paucity of data exists to determine the ability of MBSR to impact clinical outcomes in asthma.

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