Publications by authors named "Danijela Semenic"

Introduction: Pyoderma gangrenosum (PG) is a neutrophilic dermatosis often associated with autoimmune disease that, despite published literature, still poses diagnostic and therapeutic challenges due to its lack of serological and histological markers and wide possibility of differential diagnosis. Although immunosuppressive therapy usually is the first-line treatment, it has a long-lasting, unpredictable treatment course, thus necessitating the need for new treatment options. This report highlights 2 cases of PG ulcers treated with different methods that show a potentially faster healing time, as well as a review of advanced treatment options for PG.

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- The aim of the study was to evaluate the efficacy and safety of the new method of platelet-rich plasma activation in the form of platelet gel, used in the treatment of non-healing chronic lower leg ulcers. The study was prospectively randomized, double blind and placebo controlled. We treated 60 patients (42 males and 18 females, mean age 69.

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Introduction: Atypical chronic wounds are challenging for clinicians because of their identification, diagnosis, and treatment. These wounds may reflect an underlying systemic or malignant disease; therefore, an accurate diagnosis and initiation of the appropriate treatment are necessary.

Case Report: A 68-year-old man presented with an atypical chronic ulcer on his left shin of 2 years' duration.

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Introduction: Fournier's gangrene is a rare but severe form of necrotizing fasciitis, primarily affecting the perianal, genital, and perineal regions. It is a rapidly progressive disease and can be potentially fatal; therefore, it should be treated as an emergency.

Case Report: Presented herein is the case of a 30-year-old man, without significant medical history, who presented to general surgery with complaints of swelling and pain in the gluteal area.

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