Concurrent Hepatoblastoma and Wilms Tumor Leading to Diagnosis of Beckwith-Wiedemann Syndrome.

Beckwith-Wiedemann syndrome (BWS) is an epigenetic overgrowth disorder and cancer predisposition syndrome caused by imprinting defects of chromosome 11p15.5-11p15.4.

State alcohol ignition interlock laws and fatal crashes.

Objective: Alcohol-impaired driving results in thousands of deaths annually. Alcohol ignition interlocks require a negative breath test to start a vehicle's engine, and 44 states have mandated some form of interlock law for drivers convicted of driving while intoxicated (DWI). The objective of this study was to estimate the association between interlock laws and fatal impaired-driving crashes.

Introgression of DNA fragments carrying resistance to fusarium head blight into cultivar Chinese Spring is associated with alteration of gene expression.

The tall wheatgrass species carries on the long arm of chromosome 7E, a locus that contributes strongly to resistance to fusarium head blight (FHB), a devastating fungal disease affecting wheat crops in all temperate areas of the world. Introgression of 7E chromatin into chromosome 7D of wheat was induced by the mutant of CS. Recombinants between chromosome 7E and wheat chromosome 7D, induced by the mutation, were monitored by a combination of molecular markers and phenotyping for FHB resistance.

Transfer of fusarium head blight resistance from to bread wheat cultivar Chinese Spring.

The diploid form of tall wheatgrass, (Host) D.R. Dewey (2 = 2 = 14, EE genome), has a high level of resistance to fusarium head blight.

Routine Surveillance Imaging Is Associated with Improved Postrelapse Survival in Patients with Ewing Sarcoma.

Children with Ewing sarcoma (ES) routinely undergo surveillance imaging after completion of therapy; however, the medical benefit of this imaging remains unclear. We aimed to determine whether there is a difference in survival between patients whose relapse was detected based on development of new symptoms or by routine imaging. We retrospectively reviewed all patients consecutively diagnosed with ES at Children's Healthcare of Atlanta from 2000 to 2011.