Synopsis of recent research by authors named "Danielle Van Westen"
- Danielle Van Westen's research primarily focuses on neurodegenerative diseases, particularly Alzheimer's disease and related conditions, investigating brain atrophy patterns, biomarkers, and structural changes using advanced imaging techniques such as MRI and diffusion-weighted spectroscopy.
- Recent findings highlight that medial temporal lobe atrophy patterns differ significantly between early- and late-onset Alzheimer's disease, and reveal specific biomarkers associated with cerebral small vessel disease that could aid in early detection and differentiation between cognitive impairments.
- The studies emphasize the importance of understanding the mechanistic underpinnings of brain alterations in neurodegenerative disorders, including functional connectivity changes linked to white matter hyperintensities, and the role of proteomic profiling in identifying commonalities across different manifestations of cerebral small vessel disease.
