Publications by authors named "Danielle S Menchaca Vega"
Presence of Phylloquinone in the Intraerythrocytic Stages of .
Rodrigo A C Sussmann Heloisa B Gabriel Alejandro García Ríos Danielle S Menchaca Vega Lydia F Yamaguchi
Front Cell Infect Microbiol
May 2022
Article Synopsis
- Malaria, a widespread parasitic disease particularly in regions like Africa and Southeast Asia, faces challenges due to drug resistance, prompting the need for new antimalarial medications.
- This study identifies phylloquinone (vitamin K1) in the malaria-causing organism, which was not previously documented, and explores the potential biosynthesis and transport mechanisms of this compound.
- The findings suggest that phylloquinone could play a significant role in the parasite's metabolism, indicating it as a potential target for developing new antimalarial drugs.
Antimalarial activity of the terpene nerolidol.
Alexandre Y Saito Adriana A Marin Rodriguez Danielle S Menchaca Vega Rodrigo A C Sussmann Emília A Kimura
Int J Antimicrob Agents
December 2016
Malaria, an infectious disease that kills more than 438,000 people per year worldwide, is a major public health problem. The emergence of strains resistant to conventional therapeutic agents necessitates the discovery of new drugs. We previously demonstrated that various substances, including terpenes, have antimalarial activity in vitro and in vivo.
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