Publications by authors named "Danielle Pannebaker"
Article Synopsis
- Plasmodium vivax is increasingly problematic in tropical regions, particularly where Plasmodium falciparum is declining, due to its ability to cause relapse infections that hinder treatment efforts.
- Researchers developed four specialized molecular inversion probe (MIP) genotyping panels targeting key genetic variations in P. vivax, aiming to better understand its population structure and resistance mechanisms.
- Analysis using these panels on 866 infections in the Peruvian Amazon revealed significant findings, including transmission networks, gene mutations related to drug resistance, and potential vaccine targets, suggesting these tools can enhance research and control of P. vivax globally.
Plasmodium falciparum infection threatens military populations deployed to highly malaria-endemic regions, such as Peruvian Army peacekeepers deployed to Central African Republic. During deployment, malaria cases were identified by microscopy and rapid diagnostic tests. After deployment, we performed malaria diagnosis by malachite green loop-mediated isothermal amplification and photo-induced electron transfer PCR assays.
View Article and Find Full Text PDFArticle Synopsis
- Transmission of malaria is on the rise in tropical regions and poses challenges for treatment, leading to relapse infections.
- Researchers developed four specialized molecular inversion probe (MIP) genotyping panels to analyze genetic variations related to antimalarial resistance and vaccines, focusing on specific SNPs.
- The study analyzed 866 malaria infections in the Peruvian Amazon, identifying key transmission networks and genetic features that could enhance malaria control efforts in other affected areas.
Parasitological and molecular detection of Trypanosoma evansi in a dog from Tocache, San Martin, Peru.
Vet Parasitol Reg Stud Reports
July 2023
This study presents the first case report of canine trypanosomiasis caused by Trypanosoma evansi in Peru. The case was admitted to a veterinary clinic in the Peruvian Amazon region of San Martin with severe clinical symptomatology which resulted in the dog's death. Microscopy screening showed the presence of trypomastigotes in blood and bone marrow and postmortem histopathology found damage at the cardiac, lung, kidney and spleen levels.
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