Response and remission in adolescent mania: signal detection analyses of the young mania rating scale.

Objective: The purpose of this study was to determine optimal criteria for defining response and remission in adolescents with acute mania.

Method: Data were analyzed from three treatment studies of adolescents with acute mania (N = 99). Trained raters completed the Young Mania Rating Scale (YMRS), and clinicians completed the Clinical Global Impressions Scale for Bipolar Disorder (CGI-BP) independent of YMRS ratings.