Extracellular DNA enhances biofilm integrity and mechanical properties of mucoid .

is one of the most common biofilm-forming pathogens responsible for lung infections of individuals with cystic fibrosis (CF). becomes tolerant to antimicrobials in the biofilm state and is difficult to treat. Production of extracellular polymeric substances (EPS), such as alginate and extracellular DNA (eDNA), can allow adherence to abiotic and biotic surfaces, antimicrobial evasion, and resilience to environmental pressures.