Too much of a good thing: Adaption to iron (II) intoxication in .

Background: There has been an increased usage of metallic antimicrobial materials to control pathogenic and multi-drug resistant bacteria. Yet, there is a corresponding need to know if this usage leads to genetic adaptations that could produce more harmful strains.

Methodology: Experimental evolution was used to adapt K-12 MG1655 to excess iron (II) with subsequent genomic analysis.