Publications by authors named "Danielle J Gardon"
Article Synopsis
- Our skin acts as a protective shield, primarily through the interfollicular epidermis, but the role of hair follicles in this process is not fully understood.
- A study using a genetic tool to disable the Abca12 gene, linked to a severe skin condition, uncovered four ways hair follicles influence skin barrier function.
- These include the upper hair follicle forming a barrier, triggering epidermal responses when disrupted, affecting sebum release, and causing hair follicle cells to migrate into the epidermis; blocking IL-17a helped ease some symptoms.
Article Synopsis
- Hair follicles play a significant role in skin barrier function, which is crucial for protection against environmental factors.
- By using a genetic tool to study the deletion of a key gene linked to a severe skin condition, researchers discovered four specific ways hair follicles influence barrier function.
- The study also highlights the potential of targeting Il17a to improve certain skin disease symptoms related to barrier dysfunction.
