Publications by authors named "Danielle H Demers"
Article Synopsis
- There is a pressing need for new treatments for infectious diseases, prompting a screening of mangrove-derived endophytic fungi as potential sources of antibiotics.
- The screening assessed the fungi's effectiveness against various bacterial pathogens and eukaryotic infectious agents, revealing that over 60% of active extracts targeted a single type of pathogen.
- The study also showed that nearly half of the fungi producing effective extracts did so only after being treated with epigenetic modulators that inhibit histone deacetylases or DNA methyltransferases.
