Propofol-sparing and hemodynamic effects of guaifenesin in sheep.

Objective: To evaluate the propofol-sparing and hemodynamic effects of guaifenesin administered for co-induction of anesthesia in sheep.

Study Design: Prospective, blinded, two-way crossover experimental study.

Animals: Thirteen healthy adult female sheep.

Heart rate, arterial pressure and propofol-sparing effects of guaifenesin in dogs.

Objective: To evaluate the heart rate (HR) and systemic arterial pressure (sAP) effects, and propofol induction dose requirements in healthy dogs administered propofol with or without guaifenesin for the induction of anesthesia.

Study Design: Prospective blinded crossover experimental study.

Animals: A total of 10 healthy adult female Beagle dogs.

Repeatability and accuracy of fingertip pulse oximeters for measurement of hemoglobin oxygen saturation in arterial blood and pulse rate in anesthetized dogs breathing 100% oxygen.

Objective: To evaluate the repeatability and accuracy of fingertip pulse oximeters (FPO) for measurement of hemoglobin oxygen saturation in arterial blood and pulse rate (PR) in anesthetized dogs breathing 100% O.

Animals: 29 healthy client-owned anesthetized dogs undergoing various surgical procedures.

Procedures: In randomized order, each of 7 FPOs or a reference pulse oximeter (PO) was applied to the tongue of each intubated anesthetized dog breathing 100% O.

Effect of intracoelomic administration of alfaxalone on the righting reflex and tactile stimulus response of common garter snakes (Thamnophis sirtalis).

Objective: To determine the intracoelemic (ICe) dose of alfaxalone required to induce loss of righting reflex (LRR) in garter snakes (Thamnophis sirtalis) and to evaluate the tactile stimulus response in unanesthetized and alfaxalone-anesthetized snakes.

Animals: 8 healthy mature garter snakes.

Procedures: During the first of 3 phases, snakes received each of 3 doses (10, 20, and 30 mg/kg) of alfaxalone, ICe, with a 2-week washout period between treatments.