Effect of an Individualized Post-Examination Instructor Remediation on Pharmacy Student Performance in a Biochemistry Course.

To assess the effectiveness of a post-examination, one-on-one instructor remediation process on student performance in a pharmacy biochemistry course by measuring the degree of score improvement on a subsequent examination. Students who scored below 70% on any examination were encouraged to meet with the course coordinator. A typical remediation session lasts about 30 minutes, and covers academic preparation, study habits, concept understanding, application, critical thinking, time management, and stress control.

Incorporation of hands-on sterile technique instruction in an introductory pharmacy practice experience.

Objective: To examine sterile technique and basic sterile compounding procedures among third-year pharmacy students.

Design: Third year pharmacy students participating in an introductory pharmacy practice experience (IPPE) in 2012 (n=126) and 2013 (n=119) performed a modified low-risk compounded sterile product (CSP) media fill challenge test, then prepared a 5 mg/mL vancomycin solution that was subsequently analyzed for accuracy.

Assessment: To identify deficiencies in sterile procedures, students were observed while performing a modified low-risk CSP media fill challenge test.

Review and recommendations for the prevention, management, and treatment of postoperative and postdischarge nausea and vomiting.

Patients have rated severe nausea to be worse than postoperative pain. The overall incidence of postoperative nausea and vomiting (PONV) is 25%-30% and can lead to delayed discharge and unanticipated hospital admission. After outpatient surgery, the overall incidence of postdischarge nausea has been reported to be 17% and of vomiting 8%, higher than nausea and vomiting reported during the procedure or recovery.

Value of pharmacy services to the healthcare system: an interdisciplinary assessment.

Objectives: The purpose of this project was to determine how pharmacists and physicians view the extending role of the hospital pharmacist in Tennessee, USA.

Methods: An 18-question survey was sent via e-mail to five selected hospitals in Tennessee. The survey was comprised of questions related to the interaction of the pharmacist with other healthcare professionals and their role in the healthcare team.

Overexpression of manganese superoxide dismutase protects against ATP depletion-mediated cell death of proximal tubule cells.

We have previously shown that in vivo renal ischemia/reperfusion results in ATP depletion, oxidant production, and manganese superoxide dismutase (MnSOD) inactivation. Current studies were designed to compare the effect of ATP depletion (Antimycin A treatment) on cell death pathways using renal proximal tubular cells and identical cells that overexpress MnSOD. ATP depletion in wild-type cells induced an apoptotic cascade that involved caspase 9 activation; MnSOD overexpressing cells afforded protection against apoptosis.

Mitochondrial targets of oxidative stress during renal ischemia/reperfusion.

Endogenous tyrosine nitration and inactivation of manganese superoxide dismutase (MnSOD) has previously been shown to occur in both human and rat chronic renal allograft rejection. To elucidate the time course of MnSOD inactivation and mitochondrial dysfunction at earlier times during renal transplantation, we developed a rodent model of renal ischemia/reperfusion (I/R). Renal function was significantly impaired at 16 h reperfusion following 30 min of warm ischemia.