Publications by authors named "Danielle Bar"
Objectives: Early initiation of biologic therapies for psoriasis has been explored to prevent or delay the onset of psoriatic arthritis (PsA). This has renewed interest in the potential role of methotrexate (MTX) in mitigating PsA risk in newly diagnosed psoriasis patients. The aim of this study was to evaluate the impact of early MTX initiation on PsA incidence in individuals with psoriasis.
View Article and Find Full Text PDFAssessing the role of wound debridement in pyoderma gangrenosum-A retrospective cohort study.
Wound Repair Regen
November 2024
Article Synopsis
- The study examined the effects of wound debridement on patients with pyoderma gangrenosum (PG), highlighting the concern of pathergy (worsening of wounds due to intervention).
- Among 104 patients analyzed, those undergoing debridement showed significantly lower remission rates (60.53%) compared to those treated with immunosuppression alone (87.88%), along with a longer average time to remission (12.3 months vs. 8.67 months).
- The results indicated higher rates of disease progression and the need for additional procedures in the debridement group, suggesting that debridement may worsen healing outcomes in PG and should be avoided in treatment.