Bone turnover is adequately suppressed in osteoporotic patients treated with bisphosphonates in daily practice.

Background: Monitoring osteoporosis therapy by measurement of bone turnover markers (BTMs) might detect non-compliance in an earlier stage of anti-osteoporosis treatment and improve persistence.

Methods: BTMs were measured in two groups. The first group consisted of patients newly diagnosed with osteoporosis and starting treatment.

Treatment with intravenous pamidronate is a good alternative in case of gastrointestinal side effects or contraindications for oral bisphosphonates.

Background: In case of contraindications or intolerance during treatment with oral bisphosphonates (OB), administration of pamidronate intravenously is a widely used alternative. In this study we compared the effect on change in bone mineral density (BMD) of the spine and hip during long term treatment with pamidronate iv in comparison to OB.

Methods: We studied 61 patients receiving treatment for at least two years.