Antileishmanial Activity of a Calophyllum brasiliense Leaf Extract.

(Clusiaceae) is a tree that grows mainly in the Atlantic Forest in Brazil. Its leaves possess antibacterial activity, cytotoxic activity against certain tumor cell lines, and antimicrobial activity in BALB/c mice infected with .Aiming to identify ultrastructural changes and DNA fragmentation in promastigotes were treated with a concentration of the dichloromethane extract and coumarin (-) mammea A/BB from leaves that inhibited 50 % of the parasites (IC), and were evaluated by transmission and scanning electron microscopy.

Antileishmanial activity of the essential oil from Tetradenia riparia obtained in different seasons.

The herbaceous shrub Tetradenia riparia has been traditionally used to treat inflammatory and infectious diseases. Recently, a study showed that T. riparia essential oil (TrEO) obtained in summer has antileishmanial effects, although these results could be influenced by seasonal variation.