Publications by authors named "Daniele Castelli"

Article Synopsis
  • The study focuses on an opportunistic pathogen that thrives in harsh environments and often leads to outbreaks in neonatal intensive care units (NICUs), primarily caused by a specific clone, referred to as the "Infectious clone."
  • It introduces a new method called hypervariable-locus melting typing (HLMT) that allows rapid detection and typing of this pathogen without the need for cultivation, achieving high accuracy with 97% specificity and 96% sensitivity compared to traditional whole genome sequencing (WGS).
  • The HLMT protocol is advantageous for large-scale environmental and clinical screenings, offering cost and time efficiency that is particularly beneficial in low- to middle-income countries.
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Sulfur degassed at volcanic arcs calls for dissolved sulfate ions (S) released by subduction-zone fluids, oxidizing (in association with carbon) the subarc mantle, but sulfur speciation in subduction fluids at subarc depths remains unclear. We apply electrolytic fluid thermodynamics to model the dissolution behavior of pyrite in metacarbonate sediments as a function of , and rock redox state up to 4.3 gigapascals and 730°C.

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A 12-year-old male neutered European Shorthair cat was presented for pruritus in the right ear region, bleeding from ear canal and a suspected polyp-like mass in its lumen.After the diagnostic imaging a biopsy of the mass was taken and submitted for histopathological evaluation. Histopathologic examination led to the diagnosis of low grade mast cell tumor.

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Urinary tract infection (UTI) is one of the most common diseases occurring in both hospitalized and community subjects. Urine culture is the gold standard test for the diagnosis of UTI, but approximately 80% are negative. The aim of this study was to evaluate the performance of the automated urinalysis system Atellica® 1500 (Siemens Healthineers, Erlangen, Germany) as screening tool for ruling out UTI.

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Pathogen typing is pivotal to detecting the emergence of high-risk clones in hospital settings and to limit their spread. Unfortunately, the most commonly used typing methods (i.e.

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carbapenemase–producing (KPC) has been endemic in Italy since 2013. In a multicenter cohort study, we investigated various aspects of KPC among patients, including 15-day mortality rates and delays in adequate therapy. Most (77%) KPC strains were sequence type (ST) ST512 or ST307.

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Some lichens were recently reported to modify the surface state of asbestos. Here we report some new insight on the physico-chemical modifications induced by natural chelators (lichen metabolites) on two asbestos samples collected in two different locations. A biomimetic approach was followed by reproducing in the laboratory the weathering effect of lichen metabolites.

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A natural deactivation of chrysotile asbestos occurs on serpentinite rocks where lichens selectively grow on the fibres and secrete metabolites, including oxalic acid, which, in the long term, turn the fibres into a non-toxic amorphous material.

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