Publications by authors named "Daniele Brinch"
Introduction: The prevalences of malnutrition and sarcopenia in patients with IBD are not precisely known, and nutritional assessment is not standardized. We assessed the prevalence and risk factors of these conditions in outpatients and their impact on clinical outcomes.
Methods: This prospective longitudinal study considered patients who had IBD for at least one year, were attending a tertiary IBD center, and were followed for the subsequent year.
Article Synopsis
- Hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN) is caused by mutations in the TTR gene, which result in misfolded proteins forming amyloid fibrils that affect the nervous system.
- A systematic genetic screening was conducted for patients with idiopathic polyneuropathy who exhibited specific "red flags," leading to the identification of ATTRv-PN in 10% of screened patients and additional cases among their relatives.
- The study concluded that early recognition through targeted screening, especially looking for symptoms like unexplained weight loss, can significantly enhance diagnosis and treatment opportunities for patients and asymptomatic carriers of ATTRv-PN.
Gastroparesis (GP) is a disorder of gastric functions that is defined by objective delayed gastric emptying in the absence of mechanical obstruction. This disease is characterized by symptoms such as nausea, post-prandial fullness, and early satiety. GP significantly impacts patients' quality of life and contributes to substantial healthcare expenses for families and society.
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