Publications by authors named "Daniela Tavares Lucena"
Monoclonal Antibodies for the Treatment of Graves Orbitopathy: Precision Medicine?
Ophthalmic Plast Reconstr Surg
July 2023
Article Synopsis
- The study reviews the use of monoclonal antibodies (Mabs) in treating Graves Orbitopathy (GO), analyzing their development, naming, and rationale behind their usage.
- A systematic review identified 76 relevant articles out of 954 screened, focusing mainly on Rituximab, Tocilizumab, and Teprotumumab, while noting that only a few clinical trials directly compared these Mabs against traditional treatments.
- The conclusion indicates uncertainty regarding the safest and most effective Mab for GO, due to the lack of direct comparisons, varying relapse rates, potential side effects, and high costs associated with these treatments.