Diplomatic culture and institutional design: Analyzing sixty years of Antarctic Treaty governance.

Since 1961 the Antarctic Treaty has been acknowledged internationally as the legitimate forum through which decision-making for the region takes place. Membership growth and the establishment of new conventions are strong indicators of how this international regime has overcome challenges to its functioning, while preserving peace maintenance, scientific cooperation and environmental protection as the main pillars of Antarctic governance. For this special volume of Annals of the Brazilian Academy of Science, this work provides an overview of the Antarctic Treaty Consultative Meetings' operation, highlighting how they established specific diplomatic practices: the progressive introduction of issues, the avoidance of contentious issues, and "watered-down", ambiguous text, all of which have enabled parties to circumvent conflict and reach consensual agreement.

Chronological Trends and Mercury Bioaccumulation in an Aquatic Semiarid Ecosystem under a Global Climate Change Scenario in the Northeastern Coast of Brazil.

Due to global warming, in the northeastern semiarid coastal regions of Brazil, regional and global drivers are responsible for decreasing continental runoff and increasing estuarine water residence time, which promotes a greater mobilization of bioavailable mercury (Hg) and allows increasing fluxes and/or bioavailability of this toxic trace element and an acceleration of biogeochemical transformation of Hg. In this work, an application of dendrochemistry analysis (annular tree rings analysis) was developed for the reconstruction of the historical pattern of mercury contamination in a contaminated area, quantifying chronological Hg contamination trends in a tropical semiarid ecosystem (Ceará River Estuary, northeastern coast of Brazil) through registration of mercury concentration on growth rings in specimens of L. and using the assessment in sediments as a support for the comparison of profiles of contamination.

Body-focused repetitive behaviors and the dermatology patient.

Body-focused repetitive behaviors (BFRBs) are psychiatric disorders that involve recurrent pulling and picking one's own body resulting in skin lesions with varying degrees of severity. For that reason, the interface with dermatology is important. Currently, the classified BFRBs are trichotillomania and excoriation disorder.

Anxiety, Gambling Activity, and Neurocognition: A Dimensional Approach to a Non-Treatment-Seeking Sample.

Background and aims Previous analyses have highlighted significant associations between gambling disorder (GD)/subsyndromal GD and increased rates of anxiety symptoms and anxiety disorders relative to the general population. However, less is known about how anxiety symptoms influence the clinical presentation of gambling problems. The objective of this study was to evaluate the association between anxiety symptoms, gambling activity, and neurocognition across the spectrum of gambling behavior.

Importance of the cutoff ratio for detecting antibodies against hepatitis A virus in oral fluids by enzyme immunoassay.

Multiple studies have examined the use of oral fluids in modified serum-based assays aiming to replace serum in antibody detection for hepatitis A. However, the reliable detection of HAV immunity in oral fluid requires an extremely sensitive assay; most immunoassays designed for serum antibody determination lack sufficient sensitivity for this purpose. Consequently, an "in-house" competitive enzyme immunoassay (EIA) designed specifically for use with oral samples collected using a ChemBio(®) device was developed to detect total anti-HAV antibodies (IgG and IgM).

The role of efflux pumps in macrolide resistance in Mycobacterium avium complex.

Mycobacteriumavium complex (MAC) is clinically important since it can cause severe infections in acquired immune deficiency syndrome (AIDS) patients and other immunocompromised individuals. Use of the macrolides clarithromycin and azithromycin has improved the outcome of MAC infections, but therapeutic failure is still a major problem. In this work, we studied efflux pump activity in MAC clinical strains and evaluated the contribution of active efflux to macrolide resistance.

Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis.

Objectives: Therapy of AIDS patients infected with Mycobacterium avium is problematic due to its intrinsic resistance to antibiotics. We have characterized the efflux pump activity of M. avium wild-type strain through an automated fluorometric method and correlated it with intrinsic resistance to antibiotics.