The aim of this study was to evaluate the occurrence of genital mycoplasmas, especially Ureaplasma parvum and Ureaplasma urealyticum, in women with atypical squamous cells of undetermined significance (ASCUS), low grade squamous intraepithelial lesions (LSIL) and high grade squamous intraepithelial lesions (HSIL), compared to women with normal cytology living in Katowice, Poland. Two sterile swabs were used to obtain material from the posterior vaginal fornix of 143 women with squamous intraepithelial lesions and 39 healthy women: first for general bacteriology, second for detection of urogenital mycoplasmas using Mycoplasma IST2 kit. From each positive Mycoplasma IST2 culture DNA was isolated and PCR was performed for identification of U.
View Article and Find Full Text PDFThe aim of this study was to evaluate microflora of the vaginal part of the cervix uteri (including high-oncogenic HPV types and C. trachomatis) in women with ASCUS, LSIL comparing with women with normal cytology. The results demonstrated that infections with high-oncogenic HPV types and C.
View Article and Find Full Text PDFDevelopment of female genito-urinary infections depends on many factors, such as immune system activity, virulence of microorganism and production of factors inhibiting the growth of microorganisms. Taking into account the possibility of relapses or severe complications, it is very important to appropriately diagnose and treat infections. Because of recently observed increase of microbial resistance to antibiotics, researchers are looking for alternatives.
View Article and Find Full Text PDFIn the nearest future cervical cancer incidence may be significantly reduced thanks to specific antiviral vaccine use. In the paper we analyzed current literature concerning human papillomavirus (HPV) infection epidemiology and possibility of prophylactic and therapeutic vaccine use.
View Article and Find Full Text PDFAtopobium vaginae was described in 1999 by Rodriguez et al. It is a Gram-positive bacterium producing organic acids (lactic acid, acetic acid, formic acid) as a results of glucose fermentation. It was first found in vaginal swab taken from a healthy woman using 16S rRNA analysis.
View Article and Find Full Text PDFObjective: The purpose of the study was to determine the frequency of C.trachomatis and HPV infections in teenage, sexually active girls.
Material And Methods: 48 non-pregnant, sexually active young women (between 16-19 years of age), who submitted for periodical check-up during oral contraceptive use.
The aim of our study was to evaluate whether in women with chlamydial cervicitis urogenital mycoplasmas and group B streptococci (GBS) colonization is found more often than among women with non-chlamydial cervicitis. This study included 351 (mean age 31.7 +/- 6.
View Article and Find Full Text PDFInfection of genito-urinary tract, caused by C. trachomatis are common worldwide. In countries, where screening diagnosis and effective treatment programmes were introduced decreasing level of infections and their complications were described.
View Article and Find Full Text PDFIn chemical plant workers producing pesticides chronic bronchitis and disturbed pulmonary ventilation are frequent. The aim of the examination of the staff (sewage-treatment plant, waste combustion plant, waste storage, industrial water pumping station)--16 males aged 21-53 years--was to assess: 1. Connective tissue metabolism--serum concentration of type I and III procollagen propeptides, collagen I telopeptide, hydroxyproline, alpha1-AP and alpha2-M antiproteases, interstitial collagenase (MMP-1) activity, as well as urine hydroxyproline and desmosine.
View Article and Find Full Text PDFObjectives: The purpose of the study was to determine the correlation between Chlamydia trachomatis, urogenital mycoplasmas and Low Grade Squamous Intraepithelial Lesions (LSIL) in women with and without Human Papilloma Virus (HPV) infection.
Materials And Methods: The specimens were tested for: carcinogenic HPV by the Hybrid Capture I Assay, Chlamydia trachomatis antigen by direct immunofluorescence, urogenital mycoplasmas by Mycoplasma IS test. Cytological smears were classified according to the Bethesda system.
Microorganisms causing respiratory system infections, mainly viruses but also bacteria, among which there are atypical such as Chlamydophila pneumoniae, play a role in etiopathogenesis of bronchial asthma. Mycoplasma pneumoniae is suggested to take part in the initiation and the bronchial asthma exacerbation. The aim of the paper was to determine the frequency of occurrence of anti-Mycoplasma pneumoniae antibodies in serum of patients suffering from bronchial asthma in comparison with the control group of healthy persons.
View Article and Find Full Text PDFChronic bacterial infections intensify the reactivity of bronchi and aggravate the course and the control of asthma. They cause the disorders of both function and the structure of respiratory epithelium. Not only structural elements of bacteria but also their toxins intensify the release of mediators of the inflammatory reaction (leucotriens, histamine, IL1, IL4, IL6, IL8, TNF alpha).
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