Immunoexpression of E-cadherin, β-catenin and Ezrin in non-small cell lung carcinomas.

Lung cancer continues to have the highest mortality rate in the world, non-small cell lung carcinoma (NSCLC) representing the most common tumor form. The therapeutic interference of the tumor intercellular adhesion disruption mechanisms can provide therapeutic targets to improve the patients' prognosis. The study included 52 cases diagnosed with NSCLC, for which the immunohistochemical expressions of E-cadherin, β-catenin and Ezrin were analyzed in relation to the epidemiological and histological prognostic parameters.