Publications by authors named "Daniela Danilova"
Article Synopsis
- Hyper IgE syndrome (STAT3-HIES), also known as Job's syndrome, results from mutations in the STAT3 gene, leading to chronic respiratory infections due to compromised pulmonary defense mechanisms.
- The study aimed to investigate how these STAT3 mutations affect the airway epithelium's ability to defend against infections, analyzing sputum properties and lung tissue from patients.
- Findings revealed that STAT3 deficiency disrupts critical airway functions, including mucus secretion and ciliary movement, contributing to increased infection risk and inflammation in patients with this syndrome.*
