Publications by authors named "Daniela Corbellini"

Objective: The interplay between arousals and respiratory events during Cheyne-Stokes respiration (CSR) with central sleep apnea (CSA) in heart failure (HF) patients is still not fully understood. We investigated the temporal relationship between arousals and CSR-CSA.

Methods: Episodes of CSR-CSA during sleep stages N1-N2 were analyzed in 22 HF patients with an apnea-hypopnea index ≥15/h, dominant CSA and central apnea index ≥5/h.

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The goal of this study was to measure arterial amino acid levels in patients with chronic heart failure (CHF), and relate them to left ventricular function and disease severity. Amino acids (AAs) play a crucial role for heart protein-energy metabolism. In heart failure, arterial AAs, which are the major determinant of AA uptake by the myocardium, are rarely measured.

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Article Synopsis
  • The study investigated if including the 6-minute walking test (6MWT) improves risk assessment for heart failure (HF) by using two clinical scores (3C-HF and MAGGIC).
  • Data from 466 HF patients showed both the clinical scores and 6MWT were effective in predicting mortality, with significant hazard ratios indicating increased risk per standard deviation changes.
  • Adding the 6MWT to the clinical scores enhanced predictive accuracy and classification of mortality risk over 12 months, particularly for patients walking less than 376 meters.
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Unlabelled: INTRODUCTION. Psychological research on Chronic Heart Failure has mainly focused on the patient's emotional status, particularly on anxiety and depression.

Aim: To describe the psychological characteristics of a sample of hospitalized CHF inpatients and to assess their illness perception and their dispositional optimism and pessimism, and the mutual relations among these variables.

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Unlabelled: In Cardiovascular Rehabilitation the increasing inpatients complexity suggests the necessity to develop screening methods which allow to identify those patients that require a psychological intervention.

Material And Methods: A Psycho-Cardiological Schedule (PCS) was developed with the aim of detecting the critical situation indicators or the presence of psychological, social and cognitive problems. The PCS, compiled by a nurse or cardiologist in collaboration with a psychologist, allows to assess the need for a deeper psychological examination, clinical and/or with tests.

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Background: We hypothesized that obese chronic heart failure (CHF) patients, who are known to have less cardiac dysfunction, could show preserved muscle protein balance. The aim of this study was to relate muscle protein balance and cardiac function to body mass index (BMI) in order to provide further insight to the obesity paradox in CHF patients.

Methods: Thirty stable CHF patients were categorized by BMI (n=6, normal; n=14, overweight; n=10, obese) and underwent post-absorptive: (i) right heart catheterization to determine cardiac hemodynamics and (ii) arterial and venous blood sampling to measure arterial and venous levels of essential amino acids (EAAs) and to calculate arterovenous differences (positive = uptake; negative = release).

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