Publications by authors named "Daniela Antenuzi"
Article Synopsis
- Previous studies indicated allelic loss in the 13q14 chromosomal region related to pituitary tumors, but the role of the RB1 gene was unclear.
- A tumor deletion map was created using samples from 43 acromegaly patients, revealing that 12% of somatotropinomas showed loss of heterozygosity in the region.
- The findings suggest that another tumor suppressor gene, not RB1, might be involved in the development of these tumors, as RB1's role was ruled out and loss of alleles occurred at similar rates in both invasive and non-invasive adenomas.
