Publications by authors named "Daniela Annenelie Bota"

Article Synopsis
  • Recurrent glioblastoma multiforme (GBM) has a poor prognosis, but the NovoTTF-100A™ System has shown improved overall survival compared to previous trials, offering a median of 9.6 months versus 6.6 months in traditional therapies.
  • Data from a post-marketing registry (PRiDe) involving 457 patients indicated that higher daily compliance and better performance status positively influenced survival rates, with higher one- and two-year survival rates compared to earlier trial results.
  • Adverse events were primarily mild to moderate skin reactions, similar to those reported in prior studies, with no new safety concerns identified.
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Radiation-induced midbrain fibrosarcoma is a rare, highly aggressive tumor, which is associated with poor prognosis. We present the case of a 48-year old man with brainstem fibrosarcoma 20 years following radiation therapy received for a pituitary tumor. We discuss this case in the context of the diagnostic criteria for these tumors, and previous reports of secondary and primary sarcomas of the central nervous system.

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