Publications by authors named "Daniel de Oliveira Miranda"
Many species from Myrtaceae have traditionally been used in traditional medicine as anti-inflammatory, antimicrobial, antidiarrheal, antioxidant and antirheumatic, besides in blood cholesterol reduction. In the present work, the anti-inflammatory activity of essential oils from eighteen Myrtaceae spp. were evaluated according to their anti-inflammatory activity in human blood, and the corresponding biomarkers were determined using untargeted metabolomics data and multivariate data analysis.
View Article and Find Full Text PDFThe phytochemical investigation of the stem bark crude extract of (Lauraceae) led to the isolation of undescribed bicyclic [3.2.1] octane neolignans, and , characterized by unusual bicyclic patterns and two other known bicyclic neolignans and .
View Article and Find Full Text PDFArticle Synopsis
- - Chagas Disease, caused by the Trypanosoma cruzi parasite, affects around seven million people globally and has limited treatment options.
- - A study tested essential oils from 18 Myrtaceae plant species for their effectiveness against T. cruzi and identified eight oils with strong anti-parasitic properties (IC <10 μg/mL, SI >10).
- - Key compounds such as (E)-caryophyllene and α-humulene were found to significantly contribute to the oils' ability to combat the parasite, highlighting the potential of these essential oils as sources of bioactive compounds.