Synthesis of novel diselenide-linked porphyrin dimers under phase-transfer catalysis condition and their interactions with DNA.

Novel diselenide-linked porphyrin dimers were synthesized under phase-transfer catalysis conditions. The targeted compounds were characterized by (1)H-NMR, high-resolution mass spectrometry, UV/VIS and fluorescence spectroscopies, redox-potential measurements, and elemental analysis. The interaction of the title compounds with DNA was studied using UV/VIS, fluorescence, and circular dichroism (CD) spectroscopies.

Novel ebselen-porphyrin conjugates: synthesis and nucleic acid interaction study.

Novel porphyrins bearing ebselen (2-phenyl-1,2-benzisoselenazol-3[2H]-one) moiety were synthesized and characterized. Their interactions with herring sperm DNA were studied by means of UV-visible, fluorescence, circular dichroism spectroscopy, and gel electrophoresis.