The unified tradeoff model.

Evidence is steadily mounting that attribute-based models offer a more accurate description of intertemporal choices than traditional alternative-based models. Among the attribute-based models, the tradeoff model offers the broadest coverage of research findings, but at the cost of considerable complexity: There now are various instantiations of the model dealing with partially overlapping universes of choice options and preference patterns. Moreover, there are reports of preference patterns in intertemporal decisions about monetary losses that contradict all attribute-based models proposed so far.

Structure and Luminescence Studies of Salts of the Helical Dication, [Au(μ-bis(diphenylphosphine)ethane)] and Comparison with Salts of [Au(μ-bis(diphenylphosphine)propane)].

Six salts ([Au(μ-dppe)](BF)·CHCl, [Au(μ-dppe)](BF)·1,2-ClCH, [Au(μ-dppe)](PF)·CHCl, [Au(μ-dppe)](PF), [Au(μ-dppe)](SbF), and [Au(μ-dppe)](OTf)·2CHCl), (dppe is bis(diphenylphosphine)ethane) containing the dication, [Au(μ-dppe)], have been prepared and structurally characterized by single-crystal X-ray crystallography. Unlike the three-coordinate dppe-bridged dimers, AuX(μ-dppe) (X = Br, I), which show considerable variation in the distance between the gold(I) ions over the range 3.0995(10) to 3.

Self-Assembled Encapsulation of CuX (X = Br, Cl) in a Gold Phosphine Box-like Cavity with Metallophilic Au-Cu Interactions.

Synthetic routes to the crystallization of two new box-like complexes, [Au(Triphos)(CuBr)](OTf)·(CHCl)·(CHOH)·(HO) () and [Au(Triphos) (CuCl)](PF)·(CHCl) () (triphos = bis(2-diphenylphosphinoethyl)phenylphosphine), have been developed. The two centrosymmetric cationic complexes have been structurally characterized through single-crystal X-ray diffraction and shown to contain a CuX (X = Br or Cl) unit suspended between two Au(I) centers without the involvement of bridging ligands. These colorless crystals display green luminescence (λ = 527 nm) for () and teal luminescence (λ = 464 nm) for ().

Thrombolytic Therapy for ST-Elevation Myocardial Infarction Presenting to non-Percutaneous Coronary Intervention Centers During the COVID-19 Crisis.

Purpose Of Review: The purpose of this review is to offer a discussion on the existing data for the use of thrombolytic therapy for the treatment of ST-elevation myocardial infarction (STEMI) as well to present an evidence-based approach regarding the treatment for STEMI patients presenting to non-percutaneous coronary intervention (PCI)-capable hospitals during the ongoing COVID-19 pandemic.

Recent Findings: There have been tremendous advances in the care of STEMI patients over the past two decades with primary (PCI) being the standard of care. However, many hospitals do not have interventional cardiology services available, and either have to expeditiously transfer patients for primary PCI, or use the strategy of fibrinolysis therapy with facilitated or rescue PCI.

Investor memory of past performance is positively biased and predicts overconfidence.

We document a memory-based mechanism associated with investor overconfidence. In Studies 1 and 2, investors were asked to recall their most important trades in the recent past and then reported investing confidence and trading frequency. After the study, they looked up and reported the actual returns of these trades.

Pharmacophore-Based Design of Phenyl-[hydroxycyclohexyl] Cycloalkyl-Carboxamide Mitofusin Activators with Improved Neuronal Activity.

Mitochondrial fragmentation from defective fusion or unopposed fission contributes to many neurodegenerative diseases. Small molecule mitofusin activators reverse mitochondrial fragmentation , promising a novel therapeutic approach. The first-in-class mitofusin activator, , has a short plasma and limited neurological system bioavailability, conferring "burst activation".

Planned Robotic Chronic Total Occlusion Percutaneous Coronary Intervention: Feasibility Report.

Background: Complex robotic percutaneous coronary intervention (R-PCI) is technically possible and leads to clinically comparable outcomes compared with the manual approach. However, there are limited data on the feasibility of chronic total occlusion (CTO) revascularization via the R-PCI approach.

Methods: Ten consecutive patients undergoing R-PCI for a coronary CTO at a single tertiary academic center were analyzed.

Unsymmetrical Coordination of Bipyridine in Three-Coordinate Gold(I) Complexes.

The unsymmetrical coordination of gold(I) by 2,2'-bipyridine (bipy) in some planar, three-coordinate cations has been examined by crystallographic and computational studies. The salts [(PhP)Au(bipy)]XF (X = P, As, Sb) form an isomorphic series in which the differences in Au-N distances range from 0.241(2) to 0.

Outcomes of fractional flow reserve-guided percutaneous coronary interventions in patients with acute coronary syndrome.

Introduction: Fractional flow reserve (FFR) assessment has been validated as an effective tool to guide revascularization of stable coronary artery disease. The role of utilizing FFR in acute coronary syndrome (ACS) is less established.

Methods: The study population was extracted from the National Readmissions Data (NRD) 2014 using International Classification of Diseases, ninth edition, clinical modification (ICD-9-CM) codes for ACS, percutaneous coronary intervention (PCI), FFR, and periprocedural complications.

Saphenous Vein Graft Aneurysm: A Case-Based Review of Percutaneous Management.

SVG aneurysms are relatively rare clinical entities most often encountered discovered as an incidental finding in patients with prior CABG surgery. There is a substantial risk of complications including rupture and death, thus surgical or percutaneous management may be considered in particular in symptomatic patients. Here, three cases are presented highlighting various percutaneous management options and considerations, including covered stent placement, coil occlusion, and a combined approach with the use of a peripheral covered stent.

Robotic-Assisted Percutaneous Coronary Intervention: Concept, Data, and Clinical Application.

The occupational hazards for interventional cardiologists include the risk of cataracts, malignancy, and orthopedic injury. Robotic technology is now available with the introduction of platforms for performing percutaneous coronary and peripheral interventions. The original remote navigation system has evolved into the current CorPath robotic system, now approved for robotic-assisted cardiovascular interventions.

The Preparation of Luminescent, Mechanochromic Molecular Containers from Non-Emissive Components: The Box Cations, [Au (Triphos) Br] and [Au (Triphos) Br ].

Two new molecular boxes, the mono-bromo box [Au (Triphos) Br](SbF ) ⋅6(CH Cl ), 4 mB, and the dibromo box, [Au (Triphos) Br ⋅H O](SbF ) ⋅4(CH Cl ), 5 dB, have been prepared in crystalline form. Although constructed from non-luminescent components, both are strongly luminescent. Like its chloro counterpart, the mono-bromo box [Au (Triphos) Br](SbF ) ⋅6(CH Cl ), 4 mB, is mechanochromic.

Complex robotic compared to manual coronary interventions: 6- and 12-month outcomes.

Objectives: To assess the long-term safety and efficacy of robotic percutaneous coronary revascularization for use in complex coronary lesions.

Background: Robotically assisted percutaneous coronary intervention (PCI) is safe and feasible in simple coronary lesions and has excellent short-term procedural and clinical outcomes for complex lesions; however, long-term safety and efficacy outcomes are unknown.

Methods: A total of 103 consecutive patients underwent a total of 108 robotic (R)-PCI procedures (age 68.

Utilization of a Nonemissive Triphosphine Ligand to Construct a Luminescent Gold(I)-Box That Undergoes Mechanochromic Collapse into a Helical Complex.

Luminescent gold(I) complexes ([Au(Triphos)Cl](PF)·2(CHCH), [Au(Triphos)Cl](AsF)·8(CHCH), and [Au(Triphos)Cl](SbF)·7(CHCH) where Triphos = bis(2-diphenylphosphinoethyl)phenylphosphine) with a boxlike architecture have been prepared and crystallographically characterized. A chloride ion resides at the center of the box with two of the six gold(I) ions nearby. Mechanical grinding of blue luminescent crystals containing the cation, [Au(Triphos)Cl], results in their conversion into amorphous solids with green emission that contain the bridged helicate cation, [μ-Cl{Au(Triphos)}].

Use of the Ocelot catheter in iliac chronic total occlusion intervention.

Purpose: The optical-coherence tomography guided Ocelot catheter has previously been shown to be a safe and effective tool for crossing peripheral chronic total occlusions. However, the existing literature focuses mostly on the superficial femoral artery, without prior evidence of use within the suprainguinal vasculature.

Case Series: We present the first known cases of the Ocelot catheter for revascularization of chronic total occlusions in the iliac vasculature.

Robotically performed excimer laser coronary atherectomy: Proof of feasibility.

The feasibility, safety, and high technical success of robotically assisted percutaneous coronary intervention (PCI) for the treatment of both simple and complex coronary disease has been demonstrated. As the current generation robotic platform is limited to a rapid exchange system, orbital or rotational atherectomy cannot be performed robotically. However, excimer laser coronary atherectomy is performed with a rapid exchange catheter but its feasibility during robotically assisted PCI is unknown.

A speed-accurate self-sustaining head direction cell path integration model without recurrent excitation.

The head direction (HD) system signals HD in an allocentric frame of reference. The system is able to update firing based on internally derived information about self-motion, a process known as path integration. Of particular interest is how path integration might maintain concordance between true HD and internally represented HD.

A Bleeding Heart: Coronary-Cameral Fistula After Septal Myomectomy.

Coronary-cameral fistulas are relatively rare communications arising within the coronary vasculature entering into one of the four cardiac chambers. This case highlights a striking angiographic example of coronary-cameral fistula occurring after septal myomectomy, a complication occurring somewhat frequently with typical spontaneous resolution.

Renal artery stenosis and ambulatory blood pressure monitoring: A case report and review of the literature.

Renal artery stenosis (RAS) is a prevalent cause of secondary hypertension. Elderly patients with atherosclerosis and young women with fibromuscular dysplasia (FMD) are particularly at risk. Blood pressure screening is often key to this diagnosis, although the reliability of clinical screening has been questioned, and ambulatory blood pressure monitoring (ABPM) likely offers superior ability to diagnose poorly controlled hypertension.

Understanding the neural basis of cognitive bias modification as a clinical treatment for depression.

Unlabelled: [Correction Notice: An Erratum for this article was reported in Vol 85(3) of (see record 2017-07144-002). In the article, there was an error in the Discussion section's first paragraph for Implications and Future Work. The in-text reference citation for Penton-Voak et al.

Formation of a Stable Complex, RuCl2(S2CPPh3)(PPh3)2, Containing an Unstable Zwitterion from the Reaction of RuCl2(PPh3)3 with Carbon Disulfide.

New insight into the complexity of the reaction of the prominent catalyst RuCl2(PPh3)3 with carbon disulfide has been obtained from a combination of X-ray diffraction and (31)P NMR studies. The red-violet compound originally formulated as a cationic π-CS2 complex, [RuCl(π-CS2)(PPh3)3]Cl, has been identified as a neutral molecule, RuCl2(S2CPPh3)(PPh3)2, which contains the unstable zwitterion S2CPPh3. In the absence of RuCl2(PPh3)3, there is no sign of a reaction between triphenylphosphine and carbon disulfide, although more basic trialkylphosphines form red adducts, S2CPR3.

Architectural constraints are a major factor reducing path integration accuracy in the rat head direction cell system.

Head direction cells fire to signal the direction in which an animal's head is pointing. They are able to track head direction using only internally-derived information (path integration)In this simulation study we investigate the factors that affect path integration accuracy. Specifically, two major limiting factors are identified: rise time, the time after stimulation it takes for a neuron to start firing, and the presence of symmetric non-offset within-layer recurrent collateral connectivity.

Shewanella oneidensis cytochrome c nitrite reductase (ccNiR) does not disproportionate hydroxylamine to ammonia and nitrite, despite a strongly favorable driving force.

Cytochrome c nitrite reductase (ccNiR) from Shewanella oneidensis, which catalyzes the six-electron reduction of nitrite to ammonia in vivo, was shown to oxidize hydroxylamine in the presence of large quantities of this substrate, yielding nitrite as the sole free nitrogenous product. UV-visible stopped-flow and rapid-freeze-quench electron paramagnetic resonance data, along with product analysis, showed that the equilibrium between hydroxylamine and nitrite is fairly rapidly established in the presence of high initial concentrations of hydroxylamine, despite said equilibrium lying far to the left. By contrast, reduction of hydroxylamine to ammonia did not occur, even though disproportionation of hydroxylamine to yield both nitrite and ammonia is strongly thermodynamically favored.

A theoretical account of cue averaging in the rodent head direction system.

Head direction (HD) cell responses are thought to be derived from a combination of internal (or idiothetic) and external (or allothetic) sources of information. Recent work from the Jeffery laboratory shows that the relative influence of visual versus vestibular inputs upon the HD cell response depends on the disparity between these sources. In this paper, we present simulation results from a model designed to explain these observations.