Diethyl phthalate and dibutyl phthalate disrupt sirtuins expression in the HepG2 cells.

Background: Phthalates are additives used as plasticizers among other uses, classified as endocrine disruptors and may contribute to some metabolic disorders. The aim of this work was to determine the effect of the exposure of diethyl phthalate (DEP) and dibutyl phthalate (DBP) on cell viability and reactive oxygen species (ROS) production, as well as the regulation of sirloins in HepG2 cells.

Methods: HepG2 cells were exposed to DEP or DBP at 0.

Insights into Some Onygenalean Fungi from Freshwater Sediments in Spain and Description of Novel Taxa.

During the course of a project investigating culturable diversity from freshwater sediments in Spain, we isolated 63 strains of cycloheximide-resistant fungi belonging to the order . These well-known ascomycetes, able to infect both humans and animals, are commonly found in terrestrial habitats, colonizing keratin-rich soils or dung. Little is known about their diversity in aquatic environments.

Two Novel Genera, and () from Freshwater Sediments and Their Global Biogeography.

Although the is one of the species-richest families in the , research into less-explored substrates can contribute to widening the knowledge of its diversity. In our ongoing survey on culturable from freshwater sediments in Spain, several pleosporacean specimens of taxonomic interest were isolated. Phylogenetic analyses based on five gene markers (ITS, LSU, , 2, and 1) revealed that these fungi represent so far undescribed lineages, which are proposed as two novel genera in the family, i.

New and interesting species of (Eurotiomycetes, Aspergillaceae) in freshwater sediments from Spain.

species are common fungi found worldwide from diverse substrates, including soil, plant debris, food products and air. Their diversity in aquatic environments is still underexplored. With the aim to explore the fungal diversity in Spanish freshwater sediments, numerous strains were isolated using various culture-dependent techniques.