[Sarcoidosis and berylliosis].

Sarcoidosis and berylliosis (chronic beryllium disease, CBD) are granulomatous diseases and are phenocopies which cannot be differentiated based on the clinical presentation. Whereas for sarcoidosis the eliciting agent is unknown, for berylliosis an exposure to beryllium (mostly as occupational exposure) can be confirmed that therefore induces a sensitization against beryllium. The diagnosis is generally made in patients with a typical clinical presentation, the histological proof of a non-necrotizing granuloma and the exclusion of other diseases causing granulomas.

Relaxation dynamics of Pd-Ni-P metallic glass: decoupling of anelastic and viscous processes.

The stress relaxation dynamics of metallic glass PdNiPwas studied in both supercooled liquid and glassy states. Time-temperature superposition was found in the metastable liquid, implying an invariant shape of the distribution of times involved in the relaxation. Once in the glass state, the distribution of relaxation times broadens as temperature and fictive temperature decrease, eventually leading to a decoupling of the relaxation in two processes.

HIF-1α, HIF-2α, and ProExC: diagnostic or prognostic relevance in conjunctival intraepithelial neoplasia?

Purpose: The aim of this study was to investigate HIF-1α, HIF-2α, and ProExC expression in conjunctival intraepithelial neoplasia (CIN), to differentiate between metaplasia and dysplasia, and to access their value as diagnostic and prognostic immunohistochemical markers. Recurrence and progression into SCC (squamous cell carcinoma) were defined as endpoints.

Methods: Forty-three specimens including CIN I (2), CIN II (9), CIN III (29), with and without metaplasia, and metaplasia alone (3), as well as 21 conjunctival control specimens, were stained with antibodies against HIF-1α, HIF-2α, and ProExC.

Increased prevalence of thrombophilia among women with severe ovarian hyperstimulation syndrome.

Objective: To determine the prevalence of markers of thrombophilia in women hospitalized for severe OHSS.

Design: Prospective study.

Setting: Academic research center.