Next Generation Copper Mediators for the Efficient Production of F-Labeled Aromatics.

Cu-mediated radiofluorination is a versatile tool for the preparation of F-labeled (hetero)aromatics. In this work, we systematically evaluated a series of complexes and identified several generally applicable mediators for highly efficient radiofluorination of aryl boronic and stannyl substrates. Utilization of these mediators in nBuOH/DMI or DMI significantly improved F-labeling yields despite use of lower precursor amounts.

Eu(O C-C≡C-CO ): An Eu Containing Anhydrous Coordination Polymer with High Stability and Negative Thermal Expansion.

Anhydrous Eu -acetylenedicarboxylate (EuADC; ADC = O C-C≡C-CO ) was synthesized by reaction of EuBr with K ADC or H ADC in degassed water under oxygen-free conditions. EuADC crystallizes in the SrADC type structure (I4 /amd, Z=4) forming a 3D coordination polymer with a diamond-like arrangement of Eu nodes (msw topology including the connecting ADC linkers). Deep orange coloured EuADC is stable in air and starts decomposing upon heating in an argon atmosphere only at 440 °C.

How Does the Fluorination of the Linker Affect the Stability of Trimesate-Based Coordination Polymers and Metal-Organic Frameworks?

The syntheses and crystal structures of the monopotassium salts of difluorinated and tri/perfluorinated trimesic acid (1,3,5-benzenetricarboxylic acid ≡ HBTC) are presented, namely, K(H dF-BTC) ( Fdd2, Z = 16) and K(H pF-BTC) ( Cc, Z = 4). For the first time, together with already known K(H mF-BTC), all fluorination degrees of trimesic acid are accessible and can be used for a systematic study of the influence of fluorination on the stability of the resulting coordination polymers and metal-organic frameworks (MOFs). The monopotassium salts show a decreasing (chemical) stability in water upon heating, as well as a decreasing thermal stability, as evidenced by differential scanning calorimetry/thermogravimetric analysis (DSC/TGA).