Publications by authors named "Daniel Ortega-Quijano"

Androgenetic alopecia, the most common cause of hair loss affecting both men and women, is typically treated using pharmaceutical options, such as minoxidil and finasteride. While these medications work for many individuals, they are not suitable options for all. To date, the only non-pharmaceutical option that the United States Food and Drug Administration has cleared as a treatment for androgenetic alopecia is low-level laser therapy (LLLT).

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Background: Androgenetic alopecia (AGA) is common. While topical minoxidil remains the only FDA-approved therapeutic for AGA, its efficacy is limited in stimulating clinically significant hair regrowth over the longer term. Oral minoxidil, which is used off-label, is a promising alternative; however, its effectiveness and underlying mechanisms warrant further investigation.

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Background: Alopecia areata is an autoimmune disease leading to nonscarring hair loss on the scalp or body. There are different treatments including immunosuppressants, hair growth stimulants, and contact immunotherapy.

Objectives: To assess the benefits and harms of the treatments for alopecia areata (AA), alopecia totalis (AT), and alopecia universalis (AU) in children and adults.

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The pathogenesis of frontal fibrosing alopecia has been linked to specific genetic variants. CYP1B1 codes for a component of the cytochrome p450 machinery that is involved in the metabolism of xenobiotic oestrogens. The study of the prevalence of polymorphisms in this gene may help to understand their role in the development of frontal fibrosing alopecia.

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Article Synopsis
  • The study investigates how biologic therapies impact cardiovascular disease risk in psoriasis patients through a systematic review and meta-analysis of placebo-controlled trials.
  • Five relevant studies were analyzed, finding no significant reduction in aortic vascular inflammation with adalimumab compared to placebo, although ustekinumab showed some benefit at 12 weeks.
  • Results indicate that while TNF-α inhibitors like adalimumab and phototherapy reduce certain blood biomarkers (CRP, IL-6), further research on actual cardiovascular events is necessary to guide clinical decisions.
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Background: There is a real possibility of successive COVID-19-epidemic waves with devastating consequences. In this context, it has become mandatory to design age-selective measures aimed at achieving an optimal balance between protecting public health and maintaining a viable economic activity.

Methods: We programmed a Susceptible, Exposed, Infected, Removed (SEIR) model in order to introduce epidemiologically relevant age classes into the outbreak-dynamics analysis.

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Background: In 2017, we carried out a cross-sectional study with the aim of describing androgenic alopecia (AGA) prescription habits among dermatologists who practice in Spain. Three years later, we repeated this study with the aim of describing the current situation and comparing it with previous data.

Material And Methods: Descriptive cross-sectional study using online questionnaires autocompleted by dermatologists working in Spain.

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low dose oral minoxidil (OM) is an increasingly used treatment for androgenetic alopecia and other types of hair loss. to analyze available data of patients treated with OM, focusing on safety and adverse effects. a search in PubMed and EMBASE was performed for studies reporting the treatment of alopecia with OM.

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This case series describes the appearance of enanthem (oral cavity lesions) in patients with COVID-19.

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