Use of Beacon v2 for Improving Genomics Based Research in a Clinical Setting.

GA4GH has proposed the Beacon architecture as an interface to retrieve genomic information which also protects the privacy of the individuals. In this paper, we propose to adapt the Beacon Reference Implementation to the use case of a study comparing the susceptibility to the carcinogenic effects of tobacco. This analysis compares the germline of heavy smokers who have either never developed lung cancer or, on the contrary, have developed it at a young age.

Providing Provenance in eHealth.

eHealth data can be generated by different health professionals. Documenting and storing the provenance of medical data will help in providing patients and medical institutions with trustable and traceable information regarding medical procedures and their results. The use of a modular architecture like HIPAMS allows covering different eHealth information representation formats as well as providing protection mechanisms and access control.

Adding Security and Privacy to Genomic Information Representation.

Provision of security and privacy to genomic data is a key issue in current genomic information representation. Existing formats do not give a solution to these issues (or they provide a partial one), so new solutions are demanded. MPEG-G (ISO/IEC 23092, Genomic Information Representation) is an International Standard for the representation of genomic information being defined by the MPEG Committee (Moving Pictures Expert Group, ISO/IEC JTC1 SC29/WG11).

Metadata to Describe Genomic Information.

Interoperable metadata is key for the management of genomic information. We propose a flexible approach that we contribute to the standardization by ISO/IEC of a new format for efficient and secure compressed storage and transmission of genomic information.

Protecting Privacy of Genomic Information.

The ISO/IEC committee in charge of standardizing the well-known MPEG audiovisual standards has launched, in cooperation with the ISO committee on Biotechnology, a new activity for efficient compressed storage and transmission of genomic information. The paper presents proposals for adding privacy and security to such in-progress standards.

Detecting determinism with improved sensitivity in time series: rank-based nonlinear predictability score.

The rank-based nonlinear predictability score was recently introduced as a test for determinism in point processes. We here adapt this measure to time series sampled from time-continuous flows. We use noisy Lorenz signals to compare this approach against a classical amplitude-based nonlinear prediction error.