Evaluation of a urine screen for acetaminophen.

Background: Acetaminophen (APAP) is a leading cause of fatal overdose. This study examined the performance characteristics of the Biosite Triage TOX Drug Screen qualitative APAP urine test (urine screen) in a clinical setting.

Methods: Paired urine and serum waste samples (collected within 2 hours of one another) were quantitatively analyzed for APAP concentration and compared to the urine screen results.