Publications by authors named "Daniel Morgado-Carrasco"
Article Synopsis
- Dark-skinned individuals (DSI) experience high rates of melasma and post-inflammatory hyperpigmentation, making sunscreen use crucial for prevention and treatment.
- A survey conducted among dermatologists and residents at an online event in Spain found that 66.6% of attendees recommend sunscreen to about 80% of DSI, with a majority also prescribing tinted versions for those with acne or melasma.
- The preferred sunscreen features included SPF ≥ 30, UVA protection, and mineral filters, with organic broad-spectrum sunscreens containing antioxidants being the most commonly recommended.
Biologics Versus JAK Inhibitors. Part II: Risk of Infections. A Narrative Review.
Dermatol Ther (Heidelb)
August 2024
Article Synopsis
- The study reviews infection risks associated with biological drugs (BD) and Janus kinase inhibitors (JAKi) specifically in dermatology, noting that while the overall infection rates are low, they remain higher than the general population.
- It highlights that certain JAKi and anti-TNF agents, particularly tofacitinib, have a greater association with infection risks, including specific infections like tuberculosis and candidiasis.
- The analysis suggests careful monitoring for patients on these treatments and calls for more long-term studies to better understand these risks.
Biologics Versus JAK Inhibitors. Part I: Cancer Risk. A Narrative Review.
Dermatol Ther (Heidelb)
June 2024
Introduction: Biological drugs (BD) and Janus kinase inhibitors (JAKi) have revolutionized the treatment of diverse dermatoses. However, there are concerns regarding their safety, especially the risk of cancer and opportunistic infections. Here, we discuss the risk of cancer associated with the BD and JAKi used in dermatology.
View Article and Find Full Text PDFUse of a 4-mm-wide double scalpel in dermatologic surgery.
Indian J Dermatol Venereol Leprol
April 2024
Article Synopsis
- Immune checkpoint inhibitors (ICI) improve cancer treatment but can trigger immune-related conditions, including dermatomyositis (DM).
- This study analyzed three DM cases linked to ICI from a patient cohort and reviewed existing literature on the topic.
- All cases were associated with specific ICI drugs and showed a strong presence of anti-TIF1γ autoantibodies, suggesting these antibodies may contribute to developing DM in some patients.
Skin of colour or pigmented skin has unique characteristics: it has a higher eumelanin-to-pheomelanin ratio, more mature melanosomes, an increased amount of melanin distributed in the upper layers of the epidermis, and more efficient DNA repair compared with lighter skin. However, individuals with skin of colour are at a significant risk of skin damage caused by ultraviolet radiation, including the development of photodermatoses and photoageing changes such as uneven skin tone, and are predisposed to pigmentary disorders. In fact, one of the most common conditions leading to dermatology consultations by patients with skin of colour is photoexacerbated pigmentary disorders.
View Article and Find Full Text PDFHigh-risk mucosal human papillomavirus-associated squamous cell carcinoma of the fingers presents distinctive clinicopathological characteristics and outcomes: a bicentric retrospective study.
Clin Exp Dermatol
March 2023
Article Synopsis
- High-risk mucosal human papillomavirus (HR-HPV) is potentially linked to cutaneous squamous cell carcinoma (cSCC) in finger tumours, with previous suggestions of genitodigital transmission needing further investigation.* -
- An observational study found HR-HPV in 33% of the cSCC cases on fingers, typically in younger patients, with tumours being smaller and more intraepidermal compared to non-HR-HPV cases.* -
- The study suggests that characteristics like basaloid morphology and absence of elastosis and inflammation can help identify HR-HPV tumours, highlighting the potential role of HR-HPV in the development of nonungual c
Dupilumab-associated Facial Erythema Successfully Treated With Oral Ivermectin.
Dermatol Pract Concept
November 2022
Melasma: The need for tailored photoprotection to improve clinical outcomes.
Photodermatol Photoimmunol Photomed
November 2022
Background/purpose: Melasma is a frequent photoexacerbated hyperpigmentary disorder, which can significantly impact on the quality of life. We sought to review the pathogenesis of melasma, and the role of photoprotection in the prevention and treatment of this disorder.
Methods: We conducted a narrative review of the literature.
Pseudoporphyria-a diagnostic challenge: A case series and a proposed diagnostic algorithm.
Photodermatol Photoimmunol Photomed
November 2022
Scabies affects more than 200 million people around the world, and causes a significant socioeconomic impact. Prolonged skin-to-skin contact is the primary mode of transmission. Fomite-mediated transmission is uncommon, although it can be significant in crusted scabies.
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